Molnupiravir, a prodrug known for its broad antiviral activity, has demonstrated efficacy in animal models of COVID-19, prompting clinical trials, in which initial results indicated a …
A García-Aguilar, R Campi-Caballero… - International Journal of …, 2023 - mdpi.com
The spike (S) protein of SARS-CoV-2 is a molecular target of great interest for developing drug therapies against COVID-19 because S is responsible for the interaction of the virus …
MV Nuli, D Bhikshapathi, AK Garige… - Separation …, 2024 - Wiley Online Library
Molnupiravir, a promising antiviral agent, has gained significant attention for its potential in treating viral infections, particularly in the context of the coronavirus disease 2019 pandemic …
AL Shiau, KH Lee, HY Cho, TH Chuang, MC Yu… - Virology, 2023 - Elsevier
Molnupiravir (MOL) is a ribonucleoside prodrug for oral treatment of COVID-19. Common adverse effects of MOL are headache, diarrhea, and nausea, which may be associated with …
R Garg, R Kumar, R Srivastava… - Medicinal Chemistry …, 2024 - Springer
The COVID-19 pandemic has been a major reason behind the increased research aimed at the identification of effective antiviral agents. Among these, Nucleoside analogs have shown …
K Fujita, O Kanai, H Hata, K Ishigami, K Nanba… - Aging and health …, 2023 - Elsevier
Background Molnupiravir is being widely used as a treatment for coronavirus disease 2019 (COVID-19); however, its acceptability and safety in older patients aged≥ 80 years in real …
A Sharma, VM Patil, M Dahiya, GP Singh… - Anti-Infective …, 2023 - ingentaconnect.com
Background: Molnupiravir is a ribonucleoside analog and exhibits its antiviral mechanism by inhibiting replication. Preclinical studies have been reported that support the role of …
LZ Bolieva, AG Malyavin, AB Vyalkova - Therapy, 2022 - modernonco.orscience.ru
Abstract The term «Long-COVID-19» refers to a condition when patients with COVID-19 suffer from long-term symptoms lasting more than 28 days from the onset of the disease. A …
Introduction. As the COVID-19 pandemic continues to pose a significant challenge to global health, effective therapeutic options for preventing and treating the disease have become …