[HTML][HTML] Paxlovid-induced symptomatic bradycardia and syncope

VM Ganipisetti, P Bollimunta, S Maringanti - Cureus, 2023 - ncbi.nlm.nih.gov
Paxlovid (nirmatrelvir/ritonavir) is a game changer in the fight against COVID-19 due to its
ease of administration and significant benefits of reducing progression to severe COVID-19 …

[HTML][HTML] Molnupiravir Revisited—Critical Assessment of Studies in Animal Models of COVID-19

HB Rasmussen, PR Hansen - Viruses, 2023 - mdpi.com
Molnupiravir, a prodrug known for its broad antiviral activity, has demonstrated efficacy in
animal models of COVID-19, prompting clinical trials, in which initial results indicated a …

[HTML][HTML] In Vitro Analysis of SARS-CoV-2 Spike Protein and Ivermectin Interaction

A García-Aguilar, R Campi-Caballero… - International Journal of …, 2023 - mdpi.com
The spike (S) protein of SARS-CoV-2 is a molecular target of great interest for developing
drug therapies against COVID-19 because S is responsible for the interaction of the virus …

Ultra‐high‐performance liquid chromatography method development for the quantification of Molnupiravir and its process‐related impurities using Box‐Behnken …

MV Nuli, D Bhikshapathi, AK Garige… - Separation …, 2024 - Wiley Online Library
Molnupiravir, a promising antiviral agent, has gained significant attention for its potential in
treating viral infections, particularly in the context of the coronavirus disease 2019 pandemic …

Molnupiravir, a ribonucleoside antiviral prodrug against SARS-CoV-2, alters the voltage-gated sodium current and causes adverse events

AL Shiau, KH Lee, HY Cho, TH Chuang, MC Yu… - Virology, 2023 - Elsevier
Molnupiravir (MOL) is a ribonucleoside prodrug for oral treatment of COVID-19. Common
adverse effects of MOL are headache, diarrhea, and nausea, which may be associated with …

Exploring nucleoside analogs: key targets in the viral life cycle-advancing strategies against SARS-CoV-2

R Garg, R Kumar, R Srivastava… - Medicinal Chemistry …, 2024 - Springer
The COVID-19 pandemic has been a major reason behind the increased research aimed at
the identification of effective antiviral agents. Among these, Nucleoside analogs have shown …

[HTML][HTML] Comparison of the acceptability and safety of molnupiravir in COVID-19 patients aged over and under 80 years

K Fujita, O Kanai, H Hata, K Ishigami, K Nanba… - Aging and health …, 2023 - Elsevier
Background Molnupiravir is being widely used as a treatment for coronavirus disease 2019
(COVID-19); however, its acceptability and safety in older patients aged≥ 80 years in real …

Role of Molnupiravir in the Treatment of COVID-19

A Sharma, VM Patil, M Dahiya, GP Singh… - Anti-Infective …, 2023 - ingentaconnect.com
Background: Molnupiravir is a ribonucleoside analog and exhibits its antiviral mechanism by
inhibiting replication. Preclinical studies have been reported that support the role of …

Persistent viral shedding of SARS-CoV-2 in pathogenesis of Long-COVID-19

LZ Bolieva, AG Malyavin, AB Vyalkova - Therapy, 2022 - modernonco.orscience.ru
Abstract The term «Long-COVID-19» refers to a condition when patients with COVID-19
suffer from long-term symptoms lasting more than 28 days from the onset of the disease. A …

[HTML][HTML] An umbrella review on treatments and therapeutic options for COVID-19

SA SeyedAlinaghi, AM Afsahi, A Molla… - Russian Journal of …, 2023 - iimmun.ru
Introduction. As the COVID-19 pandemic continues to pose a significant challenge to global
health, effective therapeutic options for preventing and treating the disease have become …