Inflammation, although necessary to fight infections, becomes a threat when it exceeds the
capability of the immune system to control it. In addition, inflammation is a cause and/or …

Introduction Despite the ever-increasing occurrences of the coronavirus disease (COVID-19)
cases around the world, very few medications have been validated in the clinical trials to …

Despite intense investigation, the pathogenesis of COVID-19 and the newly defined long
COVID-19 syndrome are not fully understood. Increasing evidence has been provided of …

The pulmonary circulation responds to hypoxia with vasoconstriction, a mechanism that
helps to adapt to short-lived hypoxic episodes. When sustained, hypoxic pulmonary …

We aimed to assess the potential role of Asymmetric dimethylarginine (ADMA) in
conditioning respiratory function and pulmonary vasoregulation during Severe Acute …

Viral infections are a continuing global burden on the human population, underscored by the
ramifications of the COVID-19 pandemic. Current treatment options and supportive therapies …

COVID-19 remains a health care concern despite the end of the pandemic. Patients with
cardiovascular disease (CVD) are at a higher risk for developing severe COVID-19 …

Linus Pauling, who was awarded the Nobel Prize in Chemistry, suggested that a high dose
of vitamin C (l-ascorbic acid) might work as a prevention or treatment for the common cold …

Pulmonary arterial hypertension (PAH) is common in severe coronavirus disease 2019
(COVID-19) and worsens the prognosis. Sildenafil, a phosphodiesterase-5 inhibitor, is …

Phosphodiesterase 5 (PDE5) inhibitors presented themselves as important players in the
nitric oxide/cGMP pathway, thus exerting a profound impact on various physiological and …