Triggering and resolution of inflammation in NASH

S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …

MAFLD: A multisystem disease

RM Pipitone, C Ciccioli, G Infantino… - Therapeutic …, 2023 - journals.sagepub.com
Nonalcoholic fatty liver disease (NAFLD), affecting about 25% of general population and
more than 50% of dysmetabolic patients, is an emerging cause of chronic liver disease and …

A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease

Z Chen, R Yu, Y Xiong, F Du, S Zhu - Lipids in health and disease, 2017 - Springer
Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of diseases, including
simple steatosis, nonalcoholic steatohepatitis (NASH), liver cirrhosis and hepatocellular …

[PDF][PDF] Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

H Tilg, AR Moschen - Hepatology, 2010 - Wiley Online Library
Whereas in most cases a fatty liver remains free of inflammation, 10%‐20% of patients who
have fatty liver develop inflammation and fibrosis (nonalcoholic steatohepatitis [NASH]) …

Adipokines and non-alcoholic fatty liver disease: multiple interactions

TE Adolph, C Grander, F Grabherr, H Tilg - International journal of …, 2017 - mdpi.com
Accumulating evidence links obesity with low-grade inflammation which may originate from
adipose tissue that secretes a plethora of pro-and anti-inflammatory cytokines termed …

Visfatin Induces Inflammation and Insulin Resistance via the NF‐κB and STAT3 Signaling Pathways in Hepatocytes

YJ Heo, SE Choi, JY Jeon, SJ Han… - Journal of diabetes …, 2019 - Wiley Online Library
Background. It has been suggested that visfatin, which is an adipocytokine, exhibits
proinflammatory properties and is associated with insulin resistance. Insulin resistance and …

Non-alcoholic fatty liver disease

BW Smith, LA Adams - Critical reviews in clinical laboratory …, 2011 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) refers to the accumulation of hepatic steatosis not
due to excess alcohol consumption. The prevalence of NAFLD is up to 30% in developed …

Unraveling the role of leptin in liver function and its relationship with liver diseases

M Martínez-Uña, Y López-Mancheño… - International journal of …, 2020 - mdpi.com
Since its discovery twenty-five years ago, the fat-derived hormone leptin has provided a
revolutionary framework for studying the physiological role of adipose tissue as an …

Role of leptin in non-alcoholic fatty liver disease

C Jiménez-Cortegana, A García-Galey, M Tami… - Biomedicines, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD), which affects about a quarter of the global
population, poses a substantial health and economic burden in all countries, yet there is no …

Pathophysiology of NAFLD and NASH in experimental models: the role of food intake regulating peptides

L Kořínková, V Pražienková, L Černá… - Frontiers in …, 2020 - frontiersin.org
Obesity, diabetes, insulin resistance, sedentary lifestyle, and Western diet are the key factors
underlying non-alcoholic fatty liver disease (NAFLD), one of the most common liver diseases …