A review of decreased sound tolerance in autism: Definitions, phenomenology, and potential mechanisms
Atypical behavioral responses to environmental sounds are common in autistic children and
adults, with 50–70% of this population exhibiting decreased sound tolerance (DST) at some …
adults, with 50–70% of this population exhibiting decreased sound tolerance (DST) at some …
Annual Research Review: Anterior Modifiers in the Emergence of Neurodevelopmental Disorders (AMEND)—a systems neuroscience approach to common …
We present the Anterior Modifiers in the Emergence of Neurodevelopmental Disorders
(AMEND) framework, designed to reframe the field of prospective studies of …
(AMEND) framework, designed to reframe the field of prospective studies of …
Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized
by core impairments in social communication as well as restricted, repetitive patterns of …
by core impairments in social communication as well as restricted, repetitive patterns of …
Sensory processing phenotypes in fragile X syndrome
Fragile X syndrome (FXS) is a neurodevelopmental disorder that causes intellectual
disability. It is a leading known genetic cause of autism. In addition to cognitive, social, and …
disability. It is a leading known genetic cause of autism. In addition to cognitive, social, and …
Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome
Identification of comparable biomarkers in humans and validated animal models will
facilitate pre-clinical to clinical therapeutic pipelines to treat neurodevelopmental disorders …
facilitate pre-clinical to clinical therapeutic pipelines to treat neurodevelopmental disorders …
[HTML][HTML] Hyperexcitability and homeostasis in fragile X syndrome
Fragile X Syndrome (FXS) is a leading inherited cause of autism and intellectual disability,
resulting from mutation in the FMR1 gene and subsequent loss of its protein product FMRP …
resulting from mutation in the FMR1 gene and subsequent loss of its protein product FMRP …
[HTML][HTML] Auditory EEG biomarkers in fragile X syndrome: clinical relevance
LE Ethridge, LA De Stefano, LM Schmitt… - Frontiers in integrative …, 2019 - frontiersin.org
Sensory hypersensitivities are common and distressing features of Fragile X Syndrome
(FXS). While there are many drug interventions that reduce behavioral deficits in Fmr1 mice …
(FXS). While there are many drug interventions that reduce behavioral deficits in Fmr1 mice …
Increased aperiodic gamma power in young boys with Fragile X Syndrome is associated with better language ability
CL Wilkinson, CA Nelson - Molecular autism, 2021 - Springer
Background The lack of robust and reliable clinical biomarkers in Fragile X Syndrome (FXS),
the most common inherited form of intellectual disability, has limited the successful …
the most common inherited form of intellectual disability, has limited the successful …
Developmental studies in fragile X syndrome
Fragile X syndrome (FXS) is the most common single gene cause of autism and intellectual
disabilities. Humans with FXS exhibit increased anxiety, sensory hypersensitivity, seizures …
disabilities. Humans with FXS exhibit increased anxiety, sensory hypersensitivity, seizures …
Cortical interneurons in autism
The mechanistic underpinnings of autism remain a subject of debate and controversy. Why
do individuals with autism share an overlapping set of atypical behaviors and symptoms …
do individuals with autism share an overlapping set of atypical behaviors and symptoms …