Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

Cancer cachexia is a systemic hypoanabolic and catabolic syndrome that diminishes the
quality of life of cancer patients, decreases the efficiency of therapeutic strategies and …

Background Chemotherapy is extensively used to treat breast cancer and is associated with
skeletal muscle deconditioning, which is known to reduce patients' quality of life, treatment …

Simple Summary In addition to cancer-related factors, anti-cancer chemotherapy treatment
can drive life-threatening body wasting in a syndrome known as cachexia. Emerging …

Background Cancer cachexia is known to adversely affect the clinical course in patients with
malignant lymphoma. The cachexia index (CXI) is a potential biomarker of cancer cachexia …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Background Skeletal muscle is sensitive to bile acids (BA) because it expresses the TGR5
receptor for BA. Cholic (CA) and deoxycholic (DCA) acids induce a sarcopenia-like …

Paraneoplastic conditions such as cancer cachexia are often exacerbated by chemotherapy,
which affects the patient's quality of life as well as the response to therapy. The aim of this …

Circadian rhythms are∼ 24 h cycles evident in behaviour, physiology and metabolism. The
molecular mechanism directing circadian rhythms is the circadian clock, which is composed …