RNA methylation modifications are closely linked to tumor development, migration, invasion
and responses to various therapies. Recent studies have shown notable advancements …

Abstract N 6-methyladenine (m 6 A) is the most common and abundant internal modification
in eukaryotic mRNAs, which can regulate gene expression and perform important biological …

Aberrant translation, a characteristic feature of cancer, is regulated by the complex and
sophisticated RNA binding proteins (RBPs) in the canonical translation machinery. N6 …

The significance of internal mRNA modifications for the modulation of transcript stability, for
regulation of nuclear export and translation efficiency, and their role in suppressing innate …

As the most common form of epigenetic regulation by RNA, N6 methyladenosine (m6A)
modification is closely involved in physiological processes, such as growth and …

SMADs are the canonical intracellular effector proteins of the TGF-β (transforming growth
factor-β). SMADs translocate from plasma membrane receptors to the nucleus regulated by …

Epitranscriptomics, the field of post-translational RNA modifications, is a burgeoning domain
of research that has recently received significant attention for its role in multiple diseases …

Senescence is the underlying mechanism of organism aging and is robustly regulated at the
post-transcriptional level. This regulation involves the chemical modifications, of which the …

The intestinal lumen acts as a critical interface connecting the external environment with the
body's internal state. It's essential to prevent the passage of harmful antigens and bacteria …

Viruses utilize host cells at all stages of their life cycle, from the transcription of genes and
translation of viral proteins to the release of viral copies. The human immune system …