Neurodegenerative disorders encompass a wide range of pathological conditions caused
by progressive damage to the neuronal cells and nervous-system connections, which …

The brain's sensitivity to oxidative stress and neuronal cell death requires effective
pharmacotherapy approaches. Current pharmacological therapies are frequently ineffective …

Alzheimer's disease is a neurodegenerative disease that affects a large proportion of older
adult people and is characterized by memory loss, progressive cognitive impairment, and …

Abstract Alzheimer's, Parkinson's, and dementia are the leading neurodegenerative
diseases that threaten the world with the aging population. Although the pathophysiology of …

Sleep deprivation (SD) has deleterious effects on cognitive functions including learning and
memory. However, some studies have shown that SD can improve cognitive functions …

The current therapeutic drugs for Alzheimer's disease only improve symptoms, they do not
delay disease progression. Therefore, there is an urgent need for new effective drugs. The …

Neurogenesis is crucial during the human lifespan for the maintenance of synaptic plasticity
and normal function. The impairment of hippocampal neurogenesis in adults may lead to …

Alzheimer's disease (AD) is the most prevalent neural disorder. However, the therapeutic
agents for AD are limited. Eucommia ulmoides Olive (EUO) is widely used as a traditional …

Postmenopausal osteoporosis (PMOP) is characterized by the uncoupling of bone
resorption and bone formation induced by estrogen deficiency, which is a complex outcome …

Since Alzheimer disease is one of the most prevalent types of dementia with a high mortality
and disability rate, so development of multi-target drugs becomes the major strategy for …