Introduction The success of the human body in fighting SARS-CoV2 infection relies on
lymphocytes and their antigen receptors. Identifying and characterizing clinically relevant …

Despite decades of antibody research, it remains challenging to predict the specificity of an
antibody solely based on its sequence. Two major obstacles are the lack of appropriate …

An important consequence of infection with a SARS-CoV-2 variant is protective humoral
immunity against other variants. However, the basis for such cross-protection at the …

Introduction A limited subset of HIV-1 infected adult individuals typically after at least 2-3
years of chronic infection, develop broadly neutralizing antibodies (bnAbs), suggesting that …

Throughout life, humans experience repeated exposure to viral antigens through infection
and vaccination, building diverse antigen-specific antibody repertoires. In recent years …

The pairing of antibody genes IGHV2-5/IGLV2-14 is established as a public immune
response that potently cross-neutralizes SARS-CoV-2 variants, including Omicron, by …

As current trend for physician tools, ChatGPT can sift through massive amounts of
information and solve problems through easy-to-understand conversations, ultimately …

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has remained a medical threat due to the evolution of multiple variants that acquire …

The antibody response to SARS-CoV-2 shows biased immunoglobulin heavy chain variable
(IGHV) gene usage, allowing definition of genetic signatures for some classes of neutralizing …

Antibodies make up an important and growing class of compounds used for the diagnosis or
treatment of disease. While traditional antibody discovery utilized immunization of animals to …