Lab-on-chip technologies for exploring the gut–immune axis in metabolic disease

AE Wheeler, V Stoeger, RM Owens - Lab on a Chip, 2024 - pubs.rsc.org
The continued rise in metabolic diseases such as obesity and type 2 diabetes mellitus poses
a global health burden, necessitating further research into factors implicated in the onset …

In vitro immunity: an overview of immunocompetent organ-on-chip models

AI Morrison, MJ Sjoerds, LA Vonk, S Gibbs… - Frontiers in …, 2024 - frontiersin.org
Impressive advances have been made to replicate human physiology in vitro over the last
few years due to the growth of the organ-on-chip (OoC) field in both industrial and academic …

Human In Vitro Models of Neuroenergetics and Neurometabolic Disturbances: Current Advances and Clinical Perspectives

J Rogal, LN Zamproni, P Nikolakopoulou… - Stem Cells …, 2024 - academic.oup.com
Neurological conditions conquer the world; they are the leading cause of disability and the
second leading cause of death worldwide, and they appear all around the world in every …

Development of Drug Efficacy Testing Platform for Glomerulonephritis

EJ Kwon, Y Choi, SY Kim, S Park, G Yun, SH Min… - Micromachines, 2024 - mdpi.com
We developed a 3D glomeruli tissue chip for glomerulonephritis (GN) testing, featuring a
gravity-driven glomerular filtration barrier (GFB) with human podocytes and endothelial cells …

Lymph Node-on-Chip Technology: Cutting-Edge Advances in Immune Microenvironment Simulation

Q Wang, Y Yang, Z Chen, B Li, Y Niu, X Li - Pharmaceutics, 2024 - mdpi.com
Organ-on-a-chip technology is attracting growing interest across various domains as a
crucial platform for drug screening and testing and is set to play a significant role in precision …

Immune response to IL6 gradient in a diffusion-based microfluidic labchip

P Sardarabadi, KY Lee, WL Sun, CH Liu - Sensors and Actuators B …, 2024 - Elsevier
Cell migration plays a crucial role in uncovering many physiological phenomena and
predicting several pathologies, such as immune cell trafficking, tissue-specific …