Transcriptional stimulation of anthrax toxin receptors by anthrax edema toxin and Bacillus anthracis Sterne spore

Q Xu, ED Hesek, M Zeng - Microbial pathogenesis, 2007 - Elsevier
We used quantitative real-time RT-PCR to not only investigate the mRNA levels of anthrax
toxin receptor 1 (ANTXR1) and 2 (ANTXR2) in the murine J774A. 1 macrophage cells and …

Decreasing the flexibility of the TELSAM-target protein linker and omitting the cleavable fusion tag improves crystal order and diffraction limits

PL Gajjar, MJP Romo, CM Litchfield, M Callahan… - bioRxiv, 2023 - biorxiv.org
TELSAM crystallization promises to become a revolutionary tool for the facile crystallization
of proteins. TELSAM can increase the rate of crystallization and form crystals at low protein …

Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1

II Salles, DE Voth, SC Ward, KM Averette… - Cellular …, 2006 - Wiley Online Library
Anthrax toxin protective antigen (PA) binds cell surface receptors (eg ANTXR1, 2), forms
heptameric pores, and translocates lethal factor (LF) or oedema factor (OF) into the …

[HTML][HTML] Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain

S Nawarathnage, YJ Tseng, S Soleimani, T Smith… - Structure, 2023 - cell.com
Human thirty-eight-negative kinase-1 (TNK1) is implicated in cancer progression. The TNK1
ubiquitin-associated (UBA) domain binds polyubiquitin and plays a regulatory role in TNK1 …

Structural diversity of a collagen-binding matrix protein from the byssus of blue mussels upon refolding

MH Suhre, T Scheibel - Journal of structural biology, 2014 - Elsevier
Blue mussels firmly adhere to a variety of different substrates by the byssus, an extracorporal
structure consisting of several protein threads. These threads are mainly composed of …

Antibodies against protective antigen and methods of use for passive immunization and treatment of anthrax

AS Kang, F Wang, I Jiang, R Sawada, W Scholz… - US Patent …, 2008 - Google Patents
(54) ANTIBODIES AGAINST PROTECTIVE 6,537,809 B2 3/2003 Brams et al. ANTIGEN AND
METHODS OF USE FOR 6,770.479 B1 8/2004 Lee et al. PASSIVE IMMUNIZATION AND …

Selection of human antibodies against cell surface-associated oligomeric anthrax protective antigen

SCJ Steiniger, LJ Altobell III, B Zhou, KD Janda - Molecular immunology, 2007 - Elsevier
The protective antigen (PA83) of Bacillus anthracis is the dominant antigen in natural and
vaccine-induced immunity to anthrax infection. Three human single-chain variable …

Anthrax hijacks host receptor

JG Bann, SJ Hultgren - Nature, 2004 - nature.com
Anthrax hijacks host receptor | Nature Skip to main content Thank you for visiting nature.com.
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[HTML][HTML] The disulfide bond Cys255-Cys279 in the immunoglobulin-like domain of anthrax toxin receptor 2 is required for membrane insertion of anthrax protective …

P Jacquez, G Avila, K Boone, A Altiyev, J Puschhof… - PloS one, 2015 - journals.plos.org
Anthrax toxin receptors act as molecular clamps or switches that control anthrax toxin entry,
pH-dependent pore formation, and translocation of enzymatic moieties across the …

[HTML][HTML] Crystal structure of Rsr, an ortholog of the antigenic Ro protein, links conformational flexibility to RNA binding activity

A Ramesh, CG Savva, A Holzenburg… - Journal of Biological …, 2007 - ASBMB
Ro ribonucleoproteins are a class of antigenic ribonucleoproteins associated with rheumatic
autoimmune diseases like systemic lupus erythematosus and Sjoögrens syndrome in …