Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen binding

JD Ramey, VA Villareal, C Ng, SC Ward, JP Xiong… - Biochemistry, 2010 - ACS Publications
Anthrax toxin receptor 1 (ANTXR1)/tumor endothelial marker 8 (TEM8) is one of two known
proteinaceous cell surface anthrax toxin receptors. A metal ion dependent adhesion site …

Characterization of TELSAM Chaperone Linker to Improve Crystallization Resolution and Structural Elucidation of the Hydrogenase Maturase Complex

PL Gajjar - 2023 - search.proquest.com
TELSAM crystallization can be a revolutionary tool for the facile crystallization of proteins.
TELSAM can increase the rate of crystallization and form crystals at low protein …

A canstatin-derived peptide provides insight into the role of capillary morphogenesis gene 2 in angiogenic regulation and matrix uptake

JG Finnell, TM Tsang, L Cryan, S Garrard… - ACS Chemical …, 2020 - ACS Publications
Capillary Morphogenesis Gene 2 protein (CMG2) is a transmembrane, integrin-like receptor
and the primary receptor for the anthrax toxin. CMG2 also plays a role in angiogenic …

Effects from metal ion in tumor endothelial marker 8 and anthrax protective antigen: BioLayer Interferometry experiment and molecular dynamics simulation study

Z Jia, C Ackroyd, T Han, V Agrawal… - Journal of …, 2017 - Wiley Online Library
One of the anthrax receptors, tumor endothelial marker 8 (TEM8), is reported to be a
potential anticancer target due to its over‐expression during tumor angiogenesis. To extend …

Roles of cellular redox factors in pathogen and toxin entry in the endocytic pathways

J Sun - Molecular regulation of endocytosis, 2012 - books.google.com
In the mind of most human beings, microbial pathogens, including viruses, bacteria, and
parasites, are the foreign invaders that cause diseases, and sometimes death. Thus …

Anthrax toxin receptor (ATR/TEM8) is highly expressed in epithelial cells lining the toxin's three sites of entry (lung, skin, and intestine)

G Bonuccelli, F Sotgia, PG Frank… - Am J Physiol Cell …, 2005 - journals.physiology.org
Anthrax is a disease caused by infection with spores from the bacteria Bacillus anthracis.
These spores enter the body, where they germinate into bacteria and secrete a tripartite …

New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus erythematosus determined by a combination of QCM-D …

A Juste-Dolz, NM do Nascimento, I Monzó… - Analytical and …, 2019 - Springer
The mechanism of self-recognition of the autoantigen TROVE2, a common biomarker in
autoimmune diseases, has been studied with a quartz crystal microbalance with dissipation …

Anthrax toxin protective antigen forms an unusual channel that unfolds and translocates proteins across membranes

BA Krantz - Electrophysiology of Unconventional Channels and …, 2015 - Springer
Anthrax toxin is one of two major virulence factors secreted by pathogenic Bacillus anthracis,
the etiologic agent of anthrax. Because inhalational anthrax is highly fatal, the agent has …

Expression and regulation of ANTXR1 in the chick embryo

D Herrmann, A Ferrer‐Vaquer, C Lahsnig… - Developmental …, 2010 - Wiley Online Library
Abstract Anthrax Toxin Receptor 1 (ANTXR1; also known as Tumor Endothelial Marker 8,
TEM8) is one of several genes that was recently found to be up‐regulated in tumor …

Expression and purification of functional human anthrax toxin receptor (ATR/TEM8) binding domain from Escherichia coli

Z Ding, KA Bradley, MA Arnaout, JP Xiong - Protein expression and …, 2006 - Elsevier
Anthrax is caused by the gram-positive, spore-forming bacterium, Bacillus anthracis. Anthrax
receptors play a crucial role in the pathogenesis of the anthrax disease. Anthrax toxin …