[PDF][PDF] High-Resolution Structure of the N-Terminal Endonuclease Domain of the Lassa Virus L
GD Wallat, Q Huang, W Wang, H Dong, H Ly - 2014 - core.ac.uk
Lassa virus (LASV) causes deadly hemorrhagic fever disease for which there are no
vaccines and limited treatments. LASV-encoded L polymerase is required for viral RNA …
vaccines and limited treatments. LASV-encoded L polymerase is required for viral RNA …
Crystal structure of amino terminal portion of influenza virus polymerase PA subunit and use thereof
Y Liu, Z Rao - US Patent 9,017,960, 2015 - Google Patents
Present invention discloses the three-dimensional crystal structure of the N-terminus
polypeptide of influenza virus polymerase subunit (PA_N of SEQ ID NO: 7). PA_N of SEQ ID …
polypeptide of influenza virus polymerase subunit (PA_N of SEQ ID NO: 7). PA_N of SEQ ID …
[图书][B] Application of fragment screening by x-ray crystallography for the identification of novel chemical scaffolds targeting viral proteins of hiv and influenza
D Patel - 2013 - search.proquest.com
Fragment-based drug discovery (FBDD) is a relatively new approach for discovery of small
molecule ligands for subsequent lead development. Here, libraries of relatively small …
molecule ligands for subsequent lead development. Here, libraries of relatively small …
Pharmacophore Mode lingand Virtual Screening to Design the Potential Influenza Virus Endonuclease Inhibitors
HS Liao, JW Wu, HL Liu, JH Zhao… - Journal of the …, 2012 - Wiley Online Library
Influenza virus endonuclease is an attractive target for antiviral therapy in the treatment of
influenza infection. The purpos e of this study is to design a novel antiviral agent with …
influenza infection. The purpos e of this study is to design a novel antiviral agent with …
[图书][B] Structural Identification and Applications of Novel Fluorescent Probes in Chemical Biology
BM Baughman - 2012 - search.proquest.com
Fluorescence spectroscopy is one of the most widely used tools in drug discovery; however,
specific criteria for compound fluorescence are not well defined. While a highly sensitive …
specific criteria for compound fluorescence are not well defined. While a highly sensitive …
[引用][C] インフルエンザウイルスのエンドヌクレアーゼドメインの結晶構造を用いた阻害剤開発及びタンパク質結晶化機構の解明
不動聡志 - 2016 - ci.nii.ac.jp
CiNii 博士論文 - インフルエンザウイルスのエンドヌクレアーゼドメインの結晶構造を用いた 阻害剤開発
及びタンパク質結晶化機構の解明 CiNii 国立情報学研究所 学術情報ナビゲータ[サイニィ] 論文・データを …
及びタンパク質結晶化機構の解明 CiNii 国立情報学研究所 学術情報ナビゲータ[サイニィ] 論文・データを …