Matrix metalloproteinases as biomarkers and therapeutic targets in colitis-associated cancer
N Sampaio Moura, A Schledwitz, M Alizadeh… - Frontiers in …, 2024 - frontiersin.org
Colorectal cancer (CRC) remains a major cause of morbidity and mortality. Therapeutic
approaches for advanced CRC are limited and rarely provide long-term benefit. Enzymes …
approaches for advanced CRC are limited and rarely provide long-term benefit. Enzymes …
Selected Cytokines and Metalloproteinases in Inflammatory Bowel Disease
B Sosna, D Aebisher, A Myśliwiec… - International Journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a collective term for two diseases: ulcerative colitis (UC)
and Crohn's disease (CD). There are many factors, eg, genetic, environmental and …
and Crohn's disease (CD). There are many factors, eg, genetic, environmental and …
RNA Expression of MMP12 Is Strongly Associated with Inflammatory Bowel Disease and Is Regulated by Metabolic Pathways in RAW 264.7 Macrophages
L Arosa, M Camba-Gómez, LF Lorenzo-Martín… - International Journal of …, 2024 - mdpi.com
Macrophage metalloelastase or matrix metalloproteinase-12 (MMP12) is a macrophage-
specific proteolytic enzyme involved in the physiopathology of many inflammatory diseases …
specific proteolytic enzyme involved in the physiopathology of many inflammatory diseases …
Solving the Puzzle: Molecular Research in Inflammatory Bowel Diseases
SM Krug - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting
gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of …
gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of …
Evaluation of colorectal cancer in ulcerative colitis reveals key immune factors during its malignant transformation
J Ma, Q Wang, C Wang, C Liu, Y Yu, Q Zhao, J Ren… - 2023 - researchsquare.com
METHODS We collected single-cell transcriptome samples of 41 healthy samples, 45 UC
samples, and 148 colorectal cancer (CRC) samples from public databases. Using the UC …
samples, and 148 colorectal cancer (CRC) samples from public databases. Using the UC …