Trained immunity and reactivity of macrophages and endothelial cells

C Drummer IV, F Saaoud, Y Shao, Y Sun… - … , and vascular biology, 2021 - Am Heart Assoc
Innate immune cells can develop exacerbated immunologic response and long-term
inflammatory phenotype following brief exposure to endogenous or exogenous insults …

[HTML][HTML] Heparan sulfate proteoglycans in viral infection and treatment: a special focus on SARS-CoV-2

V De Pasquale, MS Quiccione, S Tafuri… - International Journal of …, 2021 - mdpi.com
Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of
unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core …

[HTML][HTML] Parallels in sepsis and COVID-19 conditions: implications for managing severe COVID-19

CO Olwal, NN Nganyewo, K Tapela… - Frontiers in …, 2021 - frontiersin.org
Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to
infection. Sepsis is a global burden killing~ 11 million persons annually. In December 2019 …

Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity

HM Al-Kuraishy, AI Al-Gareeb, YQ Almulaiky… - European journal of …, 2021 - Elsevier
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the responsible agent for
the coronavirus disease 2019 (Covid-19), has its entry point through interaction with …

[HTML][HTML] A machine-generated view of the role of blood glucose levels in the severity of COVID-19

E Logette, C Lorin, C Favreau, E Oshurko… - Frontiers in Public …, 2021 - frontiersin.org
SARS-CoV-2 started spreading toward the end of 2019 causing COVID-19, a disease that
reached pandemic proportions among the human population within months. The reasons for …

Role of SARS-CoV-2-induced cytokines and growth factors in coagulopathy and thromboembolism

F Ahmad, M Kannan, AW Ansari - Cytokine & Growth Factor Reviews, 2022 - Elsevier
Severe COVID-19 patients frequently present thrombotic complications which commonly
lead to multiorgan failure and increase the risk of death. Severe SARS-CoV-2 infection …

[HTML][HTML] The role of endothelium in COVID-19

M Ionescu, AP Stoian, M Rizzo, D Serban… - International Journal of …, 2021 - mdpi.com
The 2019 novel coronavirus, known as severe acute respiratory syndrome-coronavirus 2
(SARS-CoV-2) or coronavirus disease 2019 (COVID-19), is causing a global pandemic. The …

[HTML][HTML] Possible link between SARS-CoV-2 infection and Parkinson's disease: the role of toll-like receptor 4

C Conte - International Journal of Molecular Sciences, 2021 - mdpi.com
Parkinson's disease (PD) is the most common neurodegenerative motor disorder
characterized by selective degeneration of dopaminergic neurons in the substantia nigra …

COVID-19 and the long-term cardio-respiratory and metabolic health complications

R Ashton, P Ansdell, E Hume… - Reviews in …, 2022 - nrl.northumbria.ac.uk
Severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) transmission
continues to impact people globally. Whilst the acute symptoms and management strategies …

Clinical implications of vascular dysfunction in acute and convalescent COVID‐19: A systematic review

G Mavraganis, MA Dimopoulou… - European Journal of …, 2022 - Wiley Online Library
Background Accumulating evidence suggests that endothelial dysfunction is implicated in
the pathogenesis and severity of coronavirus disease 2019 (COVID‐19). In this context …