Prothrombotic status in COVID‑19 with diabetes mellitus

RM Mitroi, V Padureanu, A Mitrea… - Biomedical …, 2023 - spandidos-publications.com
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection has caused an
important social and health impact worldwide and the coronavirus disease‑19 (COVID‑19) …

New avenues to explore in SARS-CoV-2 Infection: Both TRIM25 and TRIM56 positively correlate with VEGF, GAS6, and sAXL in COVID-19 patients

G Baskol, M Özel, H Saracoglu, B Ulger… - Viral …, 2022 - liebertpub.com
The ongoing COVID-19 pandemic poses a significant threat to human health. Many
hypotheses regarding pathogenesis have been proposed and are being tried to be clarified …

[HTML][HTML] Acute myocardial injury in patients with COVID-19: Possible mechanisms and clinical implications

I Rusu, M Turlacu, MM Micheu - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 infection affects not only the lungs, but
also the cardiovascular system, having a major impact on patients' outcomes. Myocardial …

Molecular modeling targeting Transmembrane Serine Protease 2 (TMPRSS2) as an alternative drug target against coronaviruses

IJ dos Santos Nascimento… - Current drug …, 2022 - ingentaconnect.com
Since December 2019, the new Coronavirus disease (COVID-19) caused by the etiological
agent SARS-CoV-2 has been responsible for several cases worldwide, becoming pandemic …

[HTML][HTML] Vessel-on-a-Chip: a powerful tool for investigating endothelial COVID-19 fingerprints

O Shevchuk, S Palii, A Pak, N Chantada, N Seoane… - Cells, 2023 - mdpi.com
Coronavirus disease (COVID-19) causes various vascular and blood-related reactions,
including exacerbated responses. The role of endothelial cells in this acute response is …

[HTML][HTML] Role of endothelial cells and angiotensin converting enzyme-II in COVID-19 and brain damages post-infection

R Mehboob, JP von Kries, K Ehsan… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) causes coronavirus
disease 2019 (COVID-19), which became a pandemic in late 2019 and early 2020. Apart …

[HTML][HTML] SARS-CoV-2 and plasma hypercoagulability

E Steadman, M Fandaros, W Yin - Cellular and Molecular Bioengineering, 2021 - Springer
Hypercoagulability has emerged as a prominent consequence of COVID-19. This presents
challenges not only in the clinic, but also in thrombosis research. Health and safety …

Obesity-related inflammation and endothelial dysfunction in COVID-19: Impact on disease severity

A De Lorenzo, V Estato… - Journal of …, 2021 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has put into evidence another
pandemic–obesity. Currently, several studies have documented the association between …

Usefulness of right ventricular longitudinal shortening fraction to detect right ventricular dysfunction in acute cor pulmonale related to COVID-19

C Beyls, Y Bohbot, P Huette, T Booz, C Daumin… - … of Cardiothoracic and …, 2021 - Elsevier
Objective To compare two-dimensional–speckle tracking echocardiographic parameters (2D-
STE) and classic echocardiographic parameters of right ventricular (RV) systolic function in …

Repurposing FDA-approved drugs targeting SARS-CoV2 3CLpro: a study by applying virtual screening, molecular dynamics, MM-PBSA calculations and Covalent …

IJ Santos Nascimento, TM Aquino… - Letters in Drug …, 2022 - ingentaconnect.com
Background: Since the end of 2019, the etiologic agent SAR-CoV-2 responsible for one of
the most significant epidemics in history has caused severe global economic, social, and …