The case-control methodology is frequently used to evaluate vaccine effectiveness post-
licensure. The results of such studies provide important insight into the level of protection …

Pneumonia and diarrhea are the leading causes of child morbidity and mortality globally
and are vaccine preventable. The WHO-coordinated Global Rotavirus and Invasive Bacterial …

Background Since the widespread use of Haemophilus influenzae (Hi) type b (Hib) vaccines
among children aged< 5 years, an increase in invasive non-Hib disease incidence has been …

Despite advances in the development and introduction of vaccines against the major
bacterial causes of meningitis, the disease and its long-term after-effects remain a problem …

Adoption of new vaccines in developing countries is critical to reducing child mortality and
meeting Millennium Development Goal 4. However, such introduction has historically …

Despite rapid economic development, China has not yet incorporated into its national
childhood immunization program vaccines against Streptococcus pneumoniae and …

The health consequences of typhoid, including increasing prevalence of drug-resistant
strains, can stress healthcare systems. While vaccination is one of the most successful and …

Abstract Background. The Gambia was the first country in Africa to introduce conjugate
Haemophilus influenzae type b (Hib) vaccine, which, as in other developing countries but …

Haemophilus influenzae type b (Hib) conjugate vaccines have been underutilized globally.
We report progress in global use of Hib vaccines included in national immunization …

Haemophilus influenzae (Hi) is responsible for significant morbidity and mortality worldwide,
particularly in children under 5 years of age. In the pre-vaccine era, 95% of serious disease …