Atrial fibrillation (AF) is the most common arrhythmia in humans. AF is characterized by
irregular and increased atrial muscle activation. This high-frequency activation obliterates …

Anthracycline-induced cardiomyopathy is a leading cause of late morbidity in childhood
cancer survivors. Aberrant DNA methylation plays a role in de novo cardiovascular disease …

Protein phosphatases have emerged as critical regulators of phosphoprotein homeostasis in
settings of health and disease. Protein phosphatase 2A (PP2A) encompasses a large …

Purpose Our aims were to investigate the pathogenesis of diabetic cardiomyopathy (DCM)
and to explore the protective effect of glucagon-like peptide-1 receptor agonist (GLP-1RA) …

Radiation-Induced CardioVascular Disease (RICVD) is an important concern in thoracic
radiotherapy with complex underlying pathophysiology. Recently, we proposed DNA …

Myocardial failure is associated with adverse remodeling, including loss of cardiomyocytes,
hypertrophy, and alterations in cell–cell contacts. Striatin-interacting phosphatase and …

Adult humans respond to heart injury by forming a permanent scar, yet other vertebrates are
capable of robust and complete cardiac regeneration. Despite progress towards …

Background: Myocardial bridging (MB) is a congenital coronary artery anomaly that has
limited molecular disease state characterization. Though a large portion of individuals may …

Primary sarcomas of the jaw are very rare tumor with unclear mechanism of tumorigenesis.
Identification of genetic alterations contributes to better understanding of tumorigenesis and …

Triglyceride deposit cardiomyovasculopathy (TGCV), a rare cardiovascular disorder caused
by genetic or acquired dysfunction of adipose triglyceride lipase (ATGL), is marked by …