Renal function is highly dependent on endothelium-derived nitric oxide (NO). Several renal
disorders have been linked to impaired NO bioavailability. The enzyme that is responsible …

The peritoneal cavity is important in clinical medicine because of its use as a portal of entry
for drugs utilized in regional chemotherapy and as a means of dialysis for anephric patients …

Abstract When Furchgott, Murad, and Ignarro were honored with the Nobel prize for the
identification of nitric oxide (NO) in 1998, the therapeutic implications of this discovery could …

The volume of extracellular fluid (ECF) is maintained within narrow limits in normal human
subjects, despite day-to-day variations in dietary intake of salt and water over a wide range …

Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury.
Background Nitric oxide (NO), produced via inducible nitric oxide synthase (iNOS), is …

Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Objective: To review the assays available for measurement of nitrite and nitrate ions in body
fluids and their clinical applications. Design and Methods: Literature searches were done of …

Prolific generation of NO by inducible nitric oxide synthase (iNOS) can cause unintended
injury to host cells during glomerulonephritis and other inflammatory diseases. While much …

The pathogenesis of human acute ischemic renal failure is complex. Studies in animals
have revealed a number of factors that could contribute to the injury associated with acute …

Publisher Summary This chapter discusses the biochemistry, theories, and diseases
associated with ageing. Aging is an extremely complex, multifactorial process, and …