[HTML][HTML] The vitamin D receptor as a potential target for the treatment of age-related neurodegenerative diseases such as Alzheimer's and Parkinson's diseases: A …

W Lasoń, D Jantas, M Leśkiewicz, M Regulska… - Cells, 2023 - mdpi.com
The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …

[HTML][HTML] Neuroprotective peptides and new strategies for ischemic stroke drug discoveries

LV Dergunova, IB Filippenkov, SA Limborska… - Genes, 2023 - mdpi.com
Ischemic stroke continues to be one of the leading causes of death and disability in the adult
population worldwide. The currently used pharmacological methods for the treatment of …

[HTML][HTML] Apitherapy in Post-Ischemic Brain Neurodegeneration of Alzheimer's Disease Proteinopathy: Focus on Honey and Its Flavonoids and Phenolic Acids

R Pluta, B Miziak, SJ Czuczwar - Molecules, 2023 - mdpi.com
Neurodegeneration of the brain after ischemia is a major cause of severe, long-term
disability, dementia, and mortality, which is a global problem. These phenomena are …

Vitamin E supplementation (alone or with other antioxidants) and stroke: a meta-analysis

E Maggio, VP Bocchini, R Carnevale… - Nutrition …, 2023 - academic.oup.com
Context A previous study showed that vitamin E is effective in reducing the incidence of
myocardial infarction only when it is taken in the absence of other antioxidants. It is unclear if …

[HTML][HTML] Mechanisms associated with post-stroke depression and pharmacologic therapy

Q Zhan, F Kong - Frontiers in Neurology, 2023 - frontiersin.org
Stroke is one of the most common cerebrovascular diseases, which is the cause of long-term
mental illness and physical disability, Post-stroke depression (PSD) is the most common …

[HTML][HTML] Natural compounds efficacy in Ophthalmic Diseases: A new twist impacting ferroptosis

M Yuan, Q He, W Xiang, Y Deng, S Lin… - Biomedicine & …, 2024 - Elsevier
Ferroptosis, a distinct form of cell death, is characterized by the iron-mediated oxidation of
lipids and is finely controlled by multiple cellular metabolic pathways. These pathways …

[HTML][HTML] Role of Calcitriol and Vitamin D Receptor (VDR) Gene Polymorphisms in Alzheimer's Disease

SP Jeong, N Sharma, SSA An - International Journal of Molecular …, 2024 - mdpi.com
Alzheimer's disease (AD) is characterized by amyloid beta (Aβ) buildup and neuronal
degeneration. An association between low serum vitamin D levels and an increased risk of …

[HTML][HTML] Association between Vitamin D and Short-Term Functional Outcomes in Acute Ischemic Stroke

MS Kim, JS Lee, SJ Chung, Y Soh - Nutrients, 2023 - mdpi.com
Vitamin D (Vit D) affects musculoskeletal performance and central nervous system
neuroprotection. We aimed to investigate the association between serum Vit D levels and …

[HTML][HTML] Vitamin D supplementation in later life: a systematic review of efficacy and safety in movement disorders

CN Homann, B Homann, G Ivanic… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction Nutrition plays a pivotal role in the multidisciplinary approach to rehabilitating
middle to old-aged patients with neurological diseases including movement disorders …

1, 25-D3 ameliorates ischemic brain injury by alleviating endoplasmic reticulum stress and ferroptosis: Involvement of vitamin D receptor and p53 signaling

T Song, J Li, Y Xia, S Hou, X Zhang, Y Wang - Cellular Signalling, 2024 - Elsevier
Endoplasmic reticulum stress (ERS) and ferroptosis are linked to cerebral ischemia
reperfusion injury (CIRI). The neuroprotective properties of 1α, 25-dihydroxyvitamin D3 …