Progress in microfluidics‐based exosome separation and detection technologies for diagnostic applications

S Lin, Z Yu, D Chen, Z Wang, J Miao, Q Li, D Zhang… - Small, 2020 - Wiley Online Library
Exosomes are secreted by most cell types and circulate in body fluids. Recent studies have
revealed that exosomes play a significant role in intercellular communication and are closely …

Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications

A Hazrati, S Soudi, K Malekpour, M Mahmoudi… - Biomarker …, 2022 - Springer
Exosomes, ranging in size from 30 to 150 nm as identified initially via electron microscopy in
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …

The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer

S Pordel, M Khorrami, F Saadatpour, D Rezaee… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

Exogenous and endogenous dendritic cell-derived exosomes: Lessons learned for immunotherapy and disease pathogenesis

M Elashiry, R Elsayed, CW Cutler - Cells, 2021 - mdpi.com
Immune therapeutic exosomes, derived exogenously from dendritic cells (DCs), the
'directors' of the immune response, are receiving favorable safety and tolerance profiles in …

MicroRNAs as potential regulators of immune response networks in asthma and chronic obstructive pulmonary disease

JA Cañas, JM Rodrigo-Muñoz, B Sastre… - Frontiers in …, 2021 - frontiersin.org
Chronic respiratory diseases (CRDs) are an important factor of morbidity and mortality,
accounting for approximately 6% of total deaths worldwide. The main CRDs are asthma and …

Exosomal LINC00355 derived from cancer-associated fibroblasts promotes bladder cancer cell resistance to cisplatin by regulating miR-34b-5p/ABCB1 axis

G Luo, Y Zhang, Z Wu, L Zhang… - Acta biochimica et …, 2021 - academic.oup.com
Cisplatin resistance is a major challenge for bladder cancer (BC). Evidence indicates that
exosome derived from cancer-associated fibroblasts (CAF-Exo) can promote chemotherapy …

[HTML][HTML] Exosomes in chronic respiratory diseases

B Purghè, M Manfredi, B Ragnoli, G Baldanzi… - Biomedicine & …, 2021 - Elsevier
Exosomes are nano-sized vesicles released by almost all cell types, with a central role as
mediators of intercellular communication. In addition to physiological conditions, these …

[HTML][HTML] MicroRNA-370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis

C Li, C Deng, T Zhou, J Hu, B Dai, F Yi… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Emerging evidence has suggested the functions of exosomes in allergic diseases including
asthma. By using a mouse model with asthma induced by ovalbumin (OVA), we explored the …

[HTML][HTML] Exosomal cargo: pro-angiogeneic, anti-inflammatory, and regenerative effects in ischemic and non-ischemic heart diseases–a comprehensive review

A Ahmadi, MG Ahmadabadi, A Babajani… - Biomedicine & …, 2023 - Elsevier
Heart diseases are the primary cause of mortality and morbidity worldwide which inflict a
heavy social and economic burden. Among heart diseases, most deaths are due to …

Extracellular vesicles from airway secretions: new insights in lung diseases

L Pastor, E Vera, JM Marin, D Sanz-Rubio - International journal of …, 2021 - mdpi.com
Lung diseases (LD) are one of the most common causes of death worldwide. Although it is
known that chronic airway inflammation and excessive tissue repair are processes …