Biological and medical applications of plasma-activated media, water and solutions

NK Kaushik, B Ghimire, Y Li, M Adhikari… - Biological …, 2019 - degruyter.com
Non-thermal atmospheric pressure plasma has been proposed as a new tool for various
biological and medical applications. Plasma in close proximity to cell culture media or water …

Strategic design of conquering hypoxia in tumor for advanced photodynamic therapy

C Zhang, X Hu, L Jin, L Lin, H Lin… - Advanced Healthcare …, 2023 - Wiley Online Library
Photodynamic therapy (PDT), with its advantages of high targeting, minimally invasive, and
low toxicity side effects, has been widely used in the clinical therapy of various tumors …

The role of nitric oxide in cancer: master regulator or NOt?

FH Khan, E Dervan, DD Bhattacharyya… - International journal of …, 2020 - mdpi.com
Nitric oxide (NO) is a key player in both the development and suppression of tumourigenesis
depending on the source and concentration of NO. In this review, we discuss the …

Long-term cerebral consequences of sepsis

CN Widmann, MT Heneka - The Lancet Neurology, 2014 - thelancet.com
Sepsis is a potentially fatal whole-body inflammatory state caused by severe infection, in
which a maladaptive, system-wide inflammatory response follows initial attempts to …

Copper complexes as anticancer agents

C Marzano, M Pellei, F Tisato… - Anti-Cancer Agents in …, 2009 - ingentaconnect.com
Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is
regarded as one of the most effective drugs, even if severe toxicities and drug resistance …

Nitric oxide in immunity and inflammation

JW Coleman - International immunopharmacology, 2001 - Elsevier
Nitric oxide (NO) is synthesised by many cell types involved in immunity and inflammation.
The principal enzyme involved is the inducible type-2 isoform of nitric oxide synthase (NOS …

Oxidative stress and apoptosis: impact on cancer therapy

T Ozben - Journal of pharmaceutical sciences, 2007 - Elsevier
It is well established that some chemotherapeutic agents and radiation therapy generate
reactive oxygen species (ROS) in patients during cancer therapy. Free radicals, particularly …

Role of iNOS in osteoarthritis: Pathological and therapeutic aspects

N Ahmad, MY Ansari, TM Haqqi - Journal of cellular physiology, 2020 - Wiley Online Library
Accumulating evidence suggests that inflammation has a key role in the pathogenesis of
osteoarthritis (OA). Nitric oxide (NO) has been established as one of the major inflammatory …

Small-molecule fluorophores and fluorescent probes for bioimaging

T Terai, T Nagano - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
Fluorescent compounds based on synthetic small molecules are powerful tools to visualize
biological events in living cells and organisms. Ever since the discovery of organic …

Mitochondria and reactive oxygen species: physiology and pathophysiology

S Bolisetty, EA Jaimes - International journal of molecular sciences, 2013 - mdpi.com
The air that we breathe contains nearly 21% oxygen, most of which is utilized by
mitochondria during respiration. While we cannot live without it, it was perceived as a bane …