Proteogenomic data and resources for pan-cancer analysis

Y Li, Y Dou, FDV Leprevost, Y Geffen, AP Calinawan… - Cancer cell, 2023 - cell.com
Summary The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …

[HTML][HTML] Recent advances and future perspectives on carbohydrate-based cancer vaccines and therapeutics

C Sorieul, F Papi, F Carboni, S Pecetta… - Pharmacology & …, 2022 - Elsevier
Carbohydrates are abundantly expressed on the surface of both eukaryotic and prokaryotic
cells, often as post translational modifications of proteins. Glycoproteins are recognized by …

Tailoring a multifunctional magnetic cationic metal–organic framework composite for synchronous enrichment of phosphopeptides/glycopeptides

H Qi, Z Li, J Ma, Q Jia - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Herein, for the first time, a multifunctional magnetic cationic MOF composite (Fe3O4@ ILI-
01@ Ti4+) was successfully prepared for the synchronous enrichment of phosphopeptides …

Tetrazine bioorthogonal chemistry derived in vivo imaging

G Zhao, Z Li, R Zhang, L Zhou, H Zhao… - Frontiers in Molecular …, 2022 - frontiersin.org
Bioorthogonal chemistry represents plenty of highly efficient and biocompatible reactions
that proceed selectively and rapidly in biological situations without unexpected side …

Cancer glycomics offers potential biomarkers and therapeutic targets in the framework of 3P medicine

Y Guo, W Jia, J Yang, X Zhan - Frontiers in endocrinology, 2022 - frontiersin.org
Glycosylation is one of the most important post-translational modifications (PTMs) in a
protein, and is the most abundant and diverse biopolymer in nature. Glycans are involved in …

Molecular-level architecture of Chlamydomonas reinhardtii's glycoprotein-rich cell wall

A Poulhazan, AA Arnold, F Mentink-Vigier… - Nature …, 2024 - nature.com
Microalgae are a renewable and promising biomass for large-scale biofuel, food and
nutrient production. However, their efficient exploitation depends on our knowledge of the …

[HTML][HTML] NMR chemical shift prediction and structural elucidation of linker-containing oligo-and polysaccharides using the computer program CASPER

KM Dorst, G Widmalm - Carbohydrate research, 2023 - Elsevier
Carbohydrate structures containing alkyl groups as aglycones are useful for investigating
enzyme activity and glycan-protein interactions. Moreover, linker-containing …

Characterization of Mesothelin Glycosylation in Pancreatic Cancer: Decreased Core Fucosylated Glycoforms in Pancreatic Cancer Patients' Sera

A Duran, PE Guerrero, MR Ortiz, D Pérez del Campo… - Biomedicines, 2022 - mdpi.com
Currently, there are no reliable biomarkers for the diagnosis of pancreatic cancer (PaC).
Glycoproteomic approaches that analyze the glycan determinants on specific glycoproteins …

Application of mass spectrometry in pancreatic cancer translational research

P Ge, Y Luo, H Chen, J Liu, H Guo, C Xu, J Qu… - Frontiers in …, 2021 - frontiersin.org
Pancreatic cancer (PC) is one of the most common malignant tumors in the digestive tract
worldwide, with increased morbidity and mortality. In recent years, with the development of …

Preparation of tannic acid and l-cysteine functionalized magnetic composites for synergistic enrichment of N-glycopeptides followed by mass spectrometric analysis

Y Wang, W Xu, H Xu, Q Jia - Analytical Methods, 2022 - pubs.rsc.org
Glycoprotein is involved in a variety of biological activities and has been linked to a number
of diseases. Glycopeptide enrichment prior to mass spectrometry (MS) detection is crucial to …