Synthesis, classification and properties of hydrogels: Their applications in drug delivery and agriculture
Absorbent polymers or hydrogel polymer materials have an enhanced water retention
capacity and are widely used in agriculture and medicine. The controlled release of …
capacity and are widely used in agriculture and medicine. The controlled release of …
Mucosal applications of poloxamer 407-based hydrogels: An overview
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …
Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications
Highlights•Poloxamers-based in situ gels are potential vehicles for ocular drug
delivery.•Poloxamers possess reversible thermoresponsive gelling and mucoadhesive …
delivery.•Poloxamers possess reversible thermoresponsive gelling and mucoadhesive …
Curcumin-loaded mesoporous silica nanoparticles dispersed in thermo-responsive hydrogel as potential Alzheimer disease therapy
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive and
behavioral impairment. Curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) can …
behavioral impairment. Curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) can …
An overview on thermosensitive oral gel based on poloxamer 407
Y Chen, JH Lee, M Meng, N Cui, CY Dai, Q Jia, ES Lee… - Materials, 2021 - mdpi.com
In this review, we describe the application of thermosensitive hydrogels composed of
poloxamer in medicine, especially for oral cavities. Thermosensitive hydrogels remain fluid …
poloxamer in medicine, especially for oral cavities. Thermosensitive hydrogels remain fluid …
Poloxamer-based thermoresponsive ketorolac tromethamine in situ gel preparations: Design, characterisation, toxicity and transcorneal permeation studies
ZMA Fathalla, A Vangala, M Longman… - European Journal of …, 2017 - Elsevier
This study was aimed at preparing, characterising and evaluating in situ gel formulations
based on a blend of two hydrophilic polymers ie poloxamer 407 (P407) and poloxamer 188 …
based on a blend of two hydrophilic polymers ie poloxamer 407 (P407) and poloxamer 188 …
A novel nasal almotriptan loaded solid lipid nanoparticles in mucoadhesive in situ gel formulation for brain targeting: preparation, characterization and in vivo …
This work aimed at designing efficient safe delivery system for intranasal (IN) brain targeting
of the water soluble anti-migraine drug Almotriptan malate (ALM). Solid lipid nanoparticles …
of the water soluble anti-migraine drug Almotriptan malate (ALM). Solid lipid nanoparticles …
Investigating the targeting power to brain tissues of intranasal rasagiline mesylate-loaded transferosomal in situ gel for efficient treatment of Parkinson's disease
Rasagiline mesylate (RSM) is a hydrophilic drug with poor oral bioavailability (36%)
because of hepatic first-pass metabolism. The present study focuses on delivering RSM …
because of hepatic first-pass metabolism. The present study focuses on delivering RSM …
Fabrication of an ionic-sensitive in situ gel loaded with resveratrol nanosuspensions intended for direct nose-to-brain delivery
J Hao, J Zhao, S Zhang, T Tong, Q Zhuang, K Jin… - Colloids and Surfaces B …, 2016 - Elsevier
The objective of this study was to fabricate a composite in situ gelling formulation combining
nanoparticulates and an ionic-triggered deacetylated gellan gum (DGG) matrix for …
nanoparticulates and an ionic-triggered deacetylated gellan gum (DGG) matrix for …
[HTML][HTML] Thermoresponsive systems composed of poloxamer 407 and HPMC or NaCMC: Mechanical, rheological and sol-gel transition analysis
Abstract Poloxamer 407 (polox407) is widely studied as thermogelling polymer, transitioning
to a gel state when warmed Polox407 forms weak hydrogels with rapid dissolution in excess …
to a gel state when warmed Polox407 forms weak hydrogels with rapid dissolution in excess …