Malaria infection in humans by Plasmodium species is associated with a reduction in
haemoglobin levels, frequently leading to anaemia. Plasmodium falciparum causes the most …

Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

The malaria vaccine Combination B comprises recombinant Plasmodium falciparum ring-
infected erythrocyte surface antigen and 2 merozoite surface proteins (MSP1 and MSP2) …

Seasonal malaria chemoprevention, previously known as intermittent preventive treatment
in children, is highly effective in areas with a short malaria transmission season. Here we …

The last several years have seen significant progress in the development of vaccines
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …

In the first phase III efficacy trial of the malaria vaccine SPf66 in Africa, MOIs in SPf66-and
placebo-vaccinated children were analyzed by polymerase chain reaction-restriction …

Dedicated to the memory of Professors Henry G. Kunkel and Bruce Merrifield (Rockefeller
University, New York), who introduced us to the fascinating worlds of immunology and …

Background A malaria vaccine is badly needed. SPf66 was one of the earliest vaccines
developed. It is a synthetic peptide vaccine containing antigens from the blood stages of …

Intimate Molecular Interactions of P. falciparum Merozoite Proteins Involved in Invasion of Red
Blood Cells and Their Implications for Vaccine Design | Chemical Reviews ACS ACS …

For the last decade chloroquine-resistant Plasmodium falciparum (CRPF) has spread
explosively in sub-Saharan Africa. In some areas of the continent, CRPF is so intense that …