Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Cell Type-Specific Extracellular Vesicles and Their Impact on Health and Disease

S Amin, H Massoumi, D Tewari, A Roy… - International Journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs), a diverse group of cell-derived exocytosed particles, are pivotal
in mediating intercellular communication due to their ability to selectively transfer …

Pathological role of inflammation in ocular disease progress and its targeting by mesenchymal stem cells (MSCs) and their exosome; current status and prospect

A Nouralishahi, N Fazlinejad, RDC Pecho… - … -Research and Practice, 2023 - Elsevier
Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …

Biopolymeric Innovations in Ophthalmic Surgery: Enhancing Devices and Drug Delivery Systems

KY Wu, S Khan, Z Liao, M Marchand, SD Tran - Polymers, 2024 - mdpi.com
The interface between material science and ophthalmic medicine is witnessing significant
advances with the introduction of biopolymers in medical device fabrication. This review …

The role of the JAK/STAT3 signaling pathway in acquired corneal diseases

D Song, Q Yang, X Li, K Chen, J Tong… - Experimental Eye …, 2023 - Elsevier
Acquired corneal diseases such as dry eye disease (DED), keratitis and corneal alkali burns
are significant contributors to vision impairment worldwide, and more effective and …

Lysyl oxidase like-1 deficiency in optic nerve head astrocytes elicits reactive astrocytosis and alters functional effects of astrocyte derived exosomes

HN Hariani, AK Ghosh, SM Rosen, HY Tso… - Experimental Eye …, 2024 - Elsevier
Glaucoma is a multifactorial progressive ocular pathology that manifests clinically with
damage to the optic nerve (ON) and the retina, ultimately leading to blindness. The optic …

[HTML][HTML] Exploring gellan gum-based hydrogels for regenerating human embryonic stem cells in age-related macular degeneration therapy: A literature review

MTG Moyo, T Adali, P Tulay - Regenerative Therapy, 2024 - Elsevier
Age-related macular degeneration (AMD) is a progressive ocular disease marked by the
deterioration of retinal photoreceptor cells, leading to central vision decline, predominantly …

Exploring Stem-Cell-Based Therapies for Retinal Regeneration

M Radu, DC Brănișteanu, RA Pirvulescu… - Life, 2024 - mdpi.com
The escalating prevalence of retinal diseases—notably, age-related macular degeneration
and hereditary retinal disorders—poses an intimidating challenge to ophthalmic medicine …

[HTML][HTML] Mesenchymal stem cells for repairing glaucomatous optic nerve

BY Hu, M Xin, M Chen, P Yu… - International Journal of …, 2024 - ncbi.nlm.nih.gov
Glaucoma is a common and complex neurodegenerative disease characterized by
progressive loss of retinal ganglion cells (RGCs) and axons. Currently, there is no effective …

[HTML][HTML] Utilizing the immune system to combat dry eye disease

W Whitley - 2024 - optometrytimes.com
Dry eye disease (DED) is a chronic and often progressive condition that can be a source of
frustration for patients and clinicians. 1 Finding the right combination of treatments that …