Basic principles of the virulence of Cryptococcus

O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Bioprocessing of horticultural wastes by solid-state fermentation into value-added/innovative bioproducts: a review

AF El Sheikha, RC Ray - Food Reviews International, 2023 - Taylor & Francis
Dealing with horticultural waste has become an urgent issue that coincides with the keen
desire of the world today to achieve sustainable development, but the question arises: How …

The multifunctional fungal ergosterol

ML Rodrigues - MBio, 2018 - Am Soc Microbiol
The roles of ergosterol in the regulation of membrane fluidity and structure, as well its role as
a target for the activity of antifungals, have been known for decades. Two recent studies …

Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii

E Bielska, MA Sisquella, M Aldeieg, C Birch… - Nature …, 2018 - nature.com
Abstract The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage
of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life …

Extracellular vesicles regulate biofilm formation and yeast-to-hypha differentiation in Candida albicans

L Honorato, JFD de Araujo, CC Ellis, AC Piffer… - MBio, 2022 - Am Soc Microbiol
In this study, we investigated the influence of fungal extracellular vesicles (EVs) during
biofilm formation and morphogenesis in Candida albicans. Using crystal violet staining and …

Extracellular Vesicles From Sporothrix brasiliensis Are an Important Virulence Factor That Induce an Increase in Fungal Burden in Experimental Sporotrichosis

MAK Ikeda, JRFA De Almeida, GP Jannuzzi… - Frontiers in …, 2018 - frontiersin.org
Sporotrichosis is a mycosis that affects the skin, lymphatic system and other organs in
humans and animals. The disease has a worldwide distribution, with endemic areas in …

Characteristics of Extracellular Vesicles Released by the Pathogenic Yeast-Like Fungi Candida glabrata, Candida parapsilosis and Candida tropicalis

J Karkowska-Kuleta, K Kulig, E Karnas, E Zuba-Surma… - Cells, 2020 - mdpi.com
Candida spp. yeast-like fungi are opportunistic pathogens in humans and have been
recently found to release extracellular vesicles (EVs) that are involved in many vital …

Synthesis of benzimidazole-1, 2, 4-triazole derivatives as potential antifungal agents targeting 14α-demethylase

E Guzel, U Acar Çevik, AE Evren, HE Bostancı… - ACS …, 2023 - ACS Publications
Invasive fungal infections (IFIs) are increasing as major infectious diseases around the
world, and the limited efficacy of existing medications has resulted in substantial morbidity …

The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

Extracellular Vesicles From the Dermatophyte Trichophyton interdigitale Modulate Macrophage and Keratinocyte Functions

TA Bitencourt, CP Rezende, NR Quaresemin… - Frontiers in …, 2018 - frontiersin.org
The release of biomolecules critically affects all pathogens and their establishment of
diseases. For the export of several biomolecules in diverse species, the use of extracellular …