The present study was designed to examine whether sex hormone polymorphisms proven
by GWAS are associated with endometriosis risk. Unrelated female participants totaling …

In our work, the associations of GWAS (genome-wide associative studies) impact for sex-
hormone-binding globulin (SHBG)-level SNPs with the risk of breast cancer (BC) in the …

Background Oestrone, predominantly made in fat, is the main circulating oestrogen and
important for target tissue oestradiol production in women after menopause. The present …

Objective We investigated whether low sex hormone concentrations are associated with
depression in older women. Study design This was a cross-sectional study of Australian …

The purpose of this work was to find a link between the breast cancer (BC)-risk effects of sex
hormone-binding globulin (SHBG)-associated polymorphisms and obesity. The study was …

Genetic effects can be sex-specific, particularly for traits such as testosterone, a sex
hormone. While sex-stratified analysis provides easily interpretable sex-specific effect size …

Objective The aim of the study is to map the shared genetic component and relationships
between thyroid and reproductive health traits to improve the understanding of the interplay …

While genome-wide association studies (GWAS) and positive selection scans identify
genomic loci driving human phenotypic diversity, functional validation is required to discover …

Context Chronic kidney disease (CKD) is a public health burden worldwide. Epidemiological
studies observed an association between sex hormones, including estradiol, and kidney …

Investigating novel therapeutic strategies for colorectal cancer (CRC) is imperative.
However, there is limited research on the use of drugs to target peripheral blood immune …