Multilayered 3-D nanofibrous scaffold with chondroitin sulfate sustained release as dermal substitute

A Sadeghi, MJ Fatemi, M Zandi, T Bagheri… - International Journal of …, 2022 - Elsevier
Electrospun nanofibers for skin tissue engineering applications face two main challenges.
The low thickness of electrospun mats is the main reason for their weak load-bearing …

Protein–based electrospun nanofibers: electrospinning conditions, biomedical applications, prospects, and challenges

MN Uddin, M Jobaer, SI Mahedi… - The Journal of The Textile …, 2023 - Taylor & Francis
Electrospun fibers have recently gained popularity, particularly in pharmaceutical and
biomedical applications, owing to their high surface–to–volume ratio, solubility, versatility …

Recent developments in electrospun nanofibers as delivery of phytoconstituents for wound healing

G Ajith, GP Tamilarasi, G Sabarees… - Drugs and Drug …, 2023 - mdpi.com
Wound healing is an unresolved therapeutic challenge for the medical community, as
wound assessment and management is a complex procedure involving numerous factors …

Immobilization of gelatin on the oxygen plasma-modified surface of polycaprolactone scaffolds with tunable pore structure for skin tissue engineering

F Ghorbani, M Sahranavard, A Zamanian - Journal of Polymer Research, 2020 - Springer
In this study, polycaprolactone (PCL) scaffolds were fabricated via the freeze-casting
method. Moreover, the surface of prepared constructs was modified using an oxygen plasma …

Electrospun polyurethane-gelatin artificial skin scaffold for wound healing

SS Letha, AS Kumar, NU… - The Journal of The Textile …, 2022 - Taylor & Francis
Native skin consists mainly of epidermal and dermal layers. Here in this work, we have
constructed an artificial skin scaffold mimicking the bilayered structure of the native skin …

Preparation and Characterization of Electrospun Double-layered Nanocomposites Membranes as a Carrier for Centella asiatica (L.)

C Mouro, R Fangueiro, IC Gouveia - Polymers, 2020 - mdpi.com
A wide range of naturally derived and synthetic biodegradable and biocompatible polymers
are today regarded as promising materials for improving skin regeneration. Alongside this …

Agro-industrial plant proteins in electrospun materials for biomedical application

E Zdraveva, V Gaurina Srček, K Kraljić, D Škevin… - Polymers, 2023 - mdpi.com
Plant proteins are receiving a lot of attention due to their abundance in nature, customizable
properties, biodegradability, biocompatibility, and bioactivity. As a result of global …

The human dermis as a target of nanoparticles for treating skin conditions

J Salazar, T Carmona, FC Zacconi, D Venegas-Yazigi… - Pharmaceutics, 2022 - mdpi.com
Skin has a preventive role against any damage raised by harmful microorganisms and
physical and chemical assaults from the external environment that could affect the body's …

Biomedical applications of electrospun nanofibers in the management of diabetic wounds

D Pamu, V Tallapaneni, VVSR Karri… - Drug Delivery and …, 2022 - Springer
Diabetes mellitus (DM) is a complex disease that affects almost all the body's vital organs.
Around 415 million people have been diagnosed with DM worldwide, and most of them are …

Electrospun polycaprolactone (PCL)-amnion nanofibrous membrane promotes nerve regeneration and prevents fibrosis in a rat sciatic nerve transection model

J Bai, C Liu, L Kong, S Tian, K Yu, D Tian - Frontiers in Surgery, 2022 - frontiersin.org
Functional recovery after peripheral nerve injury repair is typically unsatisfactory. An
anastomotically poor microenvironment and scarring at the repair site are important factors …