Sepsis is a common critical clinical disease with high mortality that can cause approximately
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …

Granulosa cells are essential for follicle initiation and development, and their abnormal
function or apoptosis is a crucial factor leading to follicular atresia. A state of oxidative stress …

Cellular signaling pathways involved in the maintenance of the equilibrium between cell
proliferation and apoptosis have emerged as rational targets that can be exploited in the …

Salidroside (SAL) is a phenylpropanoid glycoside monomer extracted from Rhodiola at high
altitudes. It has been proven to have protective effects on myocardial injury, liver cancer …

Tubulin-based microtubule is a core component of flagella axoneme and essential for sperm
motility and male fertility. Structural components of the axoneme have been well explored …

Purpose Pancreatic cancer (PC) is one of the most deadly human malignancies. Curcumin
is a natural polyphenolic compound with wide-ranging pharmacological effects. Growing …

Hydroxycinnamic acid derivatives (HCDs) are polyphenols that are abundant in cereals,
coffee, tea, wine, fruits, vegetables, and other plant-based foods. To aid in the clinical …

Ulcerative colitis is a chronic inflammatory disease with a remitting-relapsing clinical course,
it has evolved into a global burden given its high incidence worldwide. Cantharidin (CTD) …

Osteoarthritis (OA) is the most common chronic degenerative joint disease in middle‐aged
and elderly people, characterized by joint pain and dysfunction. Macrophages are key …

Lower back pain (LBP) is a common degenerative musculoskeletal disease that imposes a
huge economic burden on both individuals and society. With the aggravation of social aging …