Adenoviral vector vaccine platforms in the SARS-CoV-2 pandemic

SA Mendonça, R Lorincz, P Boucher, DT Curiel - npj Vaccines, 2021 - nature.com
Adenoviral vectors have been explored as vaccine agents for a range of infectious diseases,
and their ability to induce a potent and balanced immune response made them logical …

Coronavirus disease 2019 as cause of viral sepsis: a systematic review and meta-analysis

E Karakike, EJ Giamarellos-Bourboulis… - Critical care …, 2021 - journals.lww.com
Objective: Coronavirus disease 2019 is a heterogeneous disease most frequently causing
respiratory tract infection, which can induce respiratory failure and multiple organ …

CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

J Geng, L Chen, Y Yuan, K Wang, Y Wang… - Signal transduction and …, 2021 - nature.com
SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape,
compromising the effectiveness of existing vaccines and neutralizing antibodies. An in-depth …

T helper type (Th1/Th2) responses to SARS-CoV-2 and influenza A (H1N1) virus: From cytokines produced to immune responses

E Aleebrahim-Dehkordi, B Molavi, M Mokhtari… - Transplant …, 2022 - Elsevier
Cytokines produced by T helper cells (T h cells) have essential roles in the body's defense
against viruses. Type 1 T helper (Th1) cells are essential for the host defense toward …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications

MAY Al-Nesf, HB Abdesselem, I Bensmail… - Nature …, 2022 - nature.com
COVID-19 complications still present a huge burden on healthcare systems and warrant
predictive risk models to triage patients and inform early intervention. Here, we profile 893 …

Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences

A Aiello, S Najafi-Fard, D Goletti - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

Imbalanced immune response of T-cell and B-cell subsets in patients with moderate and severe COVID-19

A Golovkin, O Kalinina, V Bezrukikh, A Aquino… - Viruses, 2021 - mdpi.com
Background: The immunological changes associated with COVID-19 are largely unknown.
Methods: Patients with COVID-19 showing moderate (n= 18; SpO2> 93%, respiratory rate> …

Community-acquired bacterial coinfections and COVID-19

MJ Patton, A Gaggar, M Might… - Physiological …, 2024 - journals.physiology.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the 29
causative pathogen of Coronavirus disease 2019 (COVID-19), has resulted in over 650 30 …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …