Role of decidual natural killer cells in human pregnancy and related pregnancy complications

X Zhang, H Wei - Frontiers in immunology, 2021 - frontiersin.org
Pregnancy is a unique type of immunological process. Healthy pregnancy is associated with
a series of inflammatory events: implantation (inflammation), gestation (anti-inflammation) …

A novel review of homocysteine and pregnancy complications

C Dai, Y Fei, J Li, Y Shi, X Yang - BioMed research international, 2021 - Wiley Online Library
Homocysteine (Hct) is a substance produced in the metabolism of methionine. It is an
essential type of amino acid gained from the daily diet. Methylenetetrahydrofolate reductase …

Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study

MC Magnus, AJ Wilcox, NH Morken, CR Weinberg… - bmj, 2019 - bmj.com
Objectives To estimate the burden of miscarriage in the Norwegian population and to
evaluate the associations with maternal age and pregnancy history. Design Prospective …

Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss

C Guo, P Cai, L Jin, Q Sha, Q Yu, W Zhang, C Jiang… - Cell discovery, 2021 - nature.com
Maintaining homeostasis of the decidual immune microenvironment at the maternal–fetal
interface is essential for placentation and reproductive success. Although distinct decidual …

Leptin action in normal and pathological pregnancies

A Pérez‐Pérez, A Toro… - Journal of cellular …, 2018 - Wiley Online Library
Leptin is now considered an important signalling molecule of the reproductive system, as it
regulates the production of gonadotrophins, the blastocyst formation and implantation, the …

Hereditary thrombophilia and recurrent pregnancy loss: a systematic review and meta-analysis

X Liu, Y Chen, C Ye, D Xing, R Wu, F Li… - Human …, 2021 - academic.oup.com
SUMMARY ANSWER: Pregnant women with hereditary thrombophilia have an increased
risk of RPL, especially for pregnant women with the G1691A mutation of the factor V Leiden …

Vitamin D and its impact on maternal-fetal outcomes in pregnancy: A critical review

S Agarwal, O Kovilam, DK Agrawal - Critical reviews in food …, 2018 - Taylor & Francis
The role of vitamin D beyond its classical function in calcium homeostasis has been of
significant interest in recent years. There has been expanding research on the pleiotropic …

Unexplained recurrent miscarriage and recurrent implantation failure: is there a place for immunomodulation?

A Mekinian, J Cohen, J Alijotas‐Reig… - American Journal of …, 2016 - Wiley Online Library
To describe and analyze the benefit of immunomodulatory drugs for recurrent miscarriages
and implantation failures. The literature research was conducted in Medline, Embase and …

A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence

HL Yang, ZZ Lai, JW Shi, WJ Zhou, J Mei, JF Ye… - Autophagy, 2022 - Taylor & Francis
Massive infiltrated and enriched decidual macrophages (dMφ) have been widely regarded
as important regulators of maternal-fetal immune tolerance and trophoblast invasion …