Microbial biofilms are complex three‐dimensional structures where sessile microbes are
embedded in a polymeric extracellular matrix. Their resistance toward the host immune …

Priority question exercises are increasingly used to frame and set future research,
innovation and development agendas. They can provide an important bridge between the …

Background Candidaemia is a life‐threatening disease that is associated with high mortality,
especially in intensive care units (ICUs). The number of comprehensive studies dealing with …

Biofilm formation by the pathobiont Haemophilus influenzae is associated with human
nasopharynx colonization, otitis media in children, and chronic respiratory infections in …

Viability and vitality assays play a crucial role in assessing the effectiveness of novel
therapeutic approaches, with stain-based methods providing speed and objectivity …

Over 2.5 million prosthetic joint implantation surgeries occur annually in the United States.
Periprosthetic joint infections (PJIs), though occurring in only 1–2% of patients receiving …

Most in vitro models lack the capacity to fully probe bacterial phenotypes emerging from the
complex interactions observed in real-life environments. This is particularly true in the …

Bacterial aggregates are observed in both natural and artificial environments. In the context
of disease, aggregates have been isolated from both chronic and acute infections …