[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease

WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …

Functional connectivity discriminates epileptogenic states and predicts surgical outcome in children with drug resistant epilepsy

S Rijal, L Corona, MS Perry, E Tamilia, JR Madsen… - Scientific Reports, 2023 - nature.com
Normal brain functioning emerges from a complex interplay among regions forming
networks. In epilepsy, these networks are disrupted causing seizures. Highly connected …

Interictal EEG source connectivity to localize the epileptogenic zone in patients with drug‐resistant epilepsy: A machine learning approach

G Ntolkeras, N Makaram, M Bernabei… - …, 2024 - Wiley Online Library
Objective To deconstruct the epileptogenic networks of patients with drug‐resistant epilepsy
(DRE) using source functional connectivity (FC) analysis; unveil the FC biomarkers of the …

Interictal magnetoencephalography abnormalities to guide intracranial electrode implantation and predict surgical outcome

TW Owen, V Janiukstyte, GR Hall… - Brain …, 2023 - academic.oup.com
Intracranial EEG is the gold standard technique for epileptogenic zone localization but
requires a preconceived hypothesis of the location of the epileptogenic tissue. This …

It's About Time! Timing in Epilepsy Evaluation and Treatment

HR McKee, J Vidaurre, D Clarke, J Wagner… - Epilepsy …, 2024 - journals.sagepub.com
The 2023 American Epilepsy Society Annual Course “It's About Time” addressed timing in
epilepsy evaluation and treatment with respect to health disparity and vulnerable …

Deep Learning-Based Visual Complexity Analysis of Electroencephalography Time-Frequency Images: Can It Localize the Epileptogenic Zone in the Brain?

N Makaram, S Gupta, M Pesce, J Bolton, S Stone… - Algorithms, 2023 - mdpi.com
In drug-resistant epilepsy, a visual inspection of intracranial electroencephalography (iEEG)
signals is often needed to localize the epileptogenic zone (EZ) and guide neurosurgery. The …

Identifying epileptogenic abnormalities through spatial clustering of MEG interictal band power

TW Owen, V Janiukstyte, GR Hall, JJ Horsley… - Epilepsia …, 2023 - Wiley Online Library
Successful epilepsy surgery depends on localizing and resecting cerebral abnormalities
and networks that generate seizures. Abnormalities, however, may be widely distributed …

Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes

SJ Gascoigne, N Evans, G Hall, C Kozma… - arXiv preprint arXiv …, 2023 - arxiv.org
Delineation of seizure onset regions from EEG is important for effective surgical workup.
However, it is unknown if their complete resection is required for seizure freedom, or in other …

[HTML][HTML] Electromagnetic source imaging predicts surgical outcome in children with focal cortical dysplasia

RK Chikara, S Jahromi, E Tamilia, JR Madsen… - Clinical …, 2023 - Elsevier
Objective To evaluate the diagnostic accuracy of electromagnetic source imaging (EMSI) in
localizing spikes and predict surgical outcome in children with drug resistant epilepsy (DRE) …

[HTML][HTML] Identification of epileptic networks with graph convolutional network incorporating oscillatory activities and evoked synaptic responses

Y Dou, J Xia, M Fu, Y Cai, X Meng, Y Zhan - NeuroImage, 2023 - Elsevier
Stereoelectroencephalography (SEEG) offers unique neural data from in-depth brain
structures with fine temporal resolutions to better investigate the origin of epileptic brain …