Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …

The largest US cancer health disparity exists in prostate cancer, with Black men having more
than a two-fold increased risk of dying from prostate cancer compared to all other races. This …

Abstract In men>~ 35 years, aging is associated with perturbations in the hypothalamus-
pituitary–testicular axis and declining serum testosterone concentrations. The major …

Over the past two decades, research has revealed that genetic factors shape the propensity
for aggressive, antisocial, and violent behavior. The best-documented gene implicated in …

Background Higher endogenous testosterone levels are associated with reduced chronic
disease risk and mortality. Since the mid-20th century, there have been significant changes …

Aim The age-specific population profiles in men of circulating testosterone and its two
bioactive metabolites dihydrotestosterone (DHT) and estradiol (E2) across the adult lifespan …

The prevalence of fusions of the transmembrane protease, serine 2, gene (TMPRSS2) with
the erythroblast transformation-specific–related gene (ERG), or TMPRSS2: ERG, in prostate …

Background: Age-related changes in testosterone levels in older persons and especially in
women have not been fully explored. The objective of this study was to describe age-related …

Objectives The short QT syndrome is a cardiac channelopathy characterised by accelerated
repolarisation which manifests as a short QT interval on the ECG. The definition of a short …