What is the impact of genome-wide supported risk variants for schizophrenia and bipolar disorder on brain structure and function? A systematic review

R Gurung, DP Prata - Psychological medicine, 2015 - cambridge.org
The powerful genome-wide association studies (GWAS) revealed common mutations that
increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority …

An fMRI study of theory of mind in schizophrenic patients with “passivity” symptoms

M Brüne, S Lissek, N Fuchs, H Witthaus, S Peters… - Neuropsychologia, 2008 - Elsevier
Several studies have shown that patients with schizophrenia underactivate brain regions
involved in theory of mind relative to controls during functional brain imaging. However, in …

Social anhedonia is associated with neural abnormalities during face emotion processing

LT Germine, L Garrido, L Bruce, C Hooker - Neuroimage, 2011 - Elsevier
Human beings are social organisms with an intrinsic desire to seek and participate in social
interactions. Social anhedonia is a personality trait characterized by a reduced desire for …

Mentalizing during social InterAction: A four component model

H Wu, X Liu, CC Hagan, D Mobbs - Cortex, 2020 - Elsevier
Mentalizing, conventionally defined as the process in which we infer the inner thoughts and
intentions of others, is a fundamental component of human social cognition. Yet its role, and …

A functional magnetic resonance imaging study of social cognition in schizophrenia during an acute episode and after recovery

KH Lee, WH Brown, PN Egleston… - American Journal of …, 2006 - Am Psychiatric Assoc
Objective: Difficulty with social interactions is a characteristic of schizophrenia. The authors
used functional magnetic resonance imaging (fMRI) to investigate brain activation changes …

The neuroanatomical basis of affective mentalizing in schizophrenia: comparison of patients with schizophrenia and patients with localized prefrontal lesions

SG Shamay-Tsoory, J Aharon-Peretz… - Schizophrenia research, 2007 - Elsevier
Patients with schizophrenia show impaired emotional and social behavior, such as
misinterpretation of social situations and lack of Theory of Mind (ToM). However, the …

What do you have in mind? Measures to assess mental state reasoning in neuropsychiatric populations

CM Eddy - Frontiers in psychiatry, 2019 - frontiersin.org
Social interaction is closely associated with both functional capacity and well-being.
Previous research has not only revealed evidence of social dysfunction in individuals with a …

Association between polygenic risk for schizophrenia, neurocognition and social cognition across development

L Germine, EB Robinson, JW Smoller… - Translational …, 2016 - nature.com
Breakthroughs in genomics have begun to unravel the genetic architecture of schizophrenia
risk, providing methods for quantifying schizophrenia polygenic risk based on common …

Neural correlates of theory of mind and empathy in schizophrenia: An activation likelihood estimation meta-analysis

K Vucurovic, S Caillies, A Kaladjian - Journal of psychiatric research, 2020 - Elsevier
Social cognition impairment predicts social functioning in schizophrenia. Several studies
have found abnormal brain activation in patients with schizophrenia during social cognition …

An fMRI study of “theory of mind” in at-risk states of psychosis: comparison with manifest schizophrenia and healthy controls

M Brüne, S Özgürdal, N Ansorge, HG von Reventlow… - Neuroimage, 2011 - Elsevier
OBJECTIVE: Poor social functioning is a hallmark of schizophrenia and may precede the
onset of illness. One of the most robust predictors of social impairment is a deficit in the …