[HTML][HTML] The effects of the COVID-19 pandemic on the elderly: A systematic review

M Moradi, E Navab, F Sharifi, B Namadi… - Iranian Journal of …, 2021 - salmandj.uswr.ac.ir
3. Results The results of the selected studies were extracted and the effects of COVID-19
pandemic on the elderly were explored in 8 parts, as follows: why COVID-19 is more …

[HTML][HTML] Senescence-associated hyper-activation to inflammatory stimuli in vitro

V Budamagunta, S Manohar-Sindhu, Y Yang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Aging is associated with an increased susceptibility to adverse inflammatory conditions such
as sepsis and cytokine storm. We hypothesized that senescent cells (SnCs) play a central …

Acute lung injury biomarkers in the prediction of COVID-19 severity: Total thiol, ferritin and lactate dehydrogenase

A Martinez Mesa, E Cabrera César, E Martín-Montañez… - Antioxidants, 2021 - mdpi.com
SARS-CoV-2 (COVID-19) patients who develop acute respiratory distress syndrome (ARDS)
can suffer acute lung injury, or even death. Early identification of severe disease is essential …

A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin

JN Justice, S Gubbi, AS Kulkarni, JM Bartley… - Geroscience, 2021 - Springer
We are in the midst of the global pandemic. Though acute respiratory coronavirus (SARS-
COV2) that leads to COVID-19 infects people of all ages, severe symptoms and mortality …

Assessing the impact of COVID-19 on the health of geriatric patients: The European GeroCovid Observational Study

C Trevisan, S Del Signore, S Fumagalli, P Gareri… - European Journal of …, 2021 - Elsevier
Background Despite the growing evidence on COVID-19, there are still many gaps in the
understanding of this disease, especially in individuals in advanced age. We describe the …

Anti-Inflammatory effects of olive leaf extract and its bioactive compounds oleacin and oleuropein-aglycone on senescent endothelial and small airway epithelial cells

A Silvestrini, C Giordani, S Bonacci, A Giuliani… - Antioxidants, 2023 - mdpi.com
Olive tree by-products have been deeply studied as an invaluable source of bioactive
compounds. Several in vitro and in vivo studies showed that olive leaf extract (OLE) has anti …

Immunosenescence and Inflammaging in COVID-19

F Asghari, A Asghary, N Majidi Zolbanin, F Faraji… - Viral …, 2023 - liebertpub.com
Despite knowledge gaps in understanding the full spectrum of the hyperinflammatory phase
caused by SARS-CoV-2, according to the World Health Organization (WHO), COVID-19 is …

The role of peroxisome proliferator-activated receptors in the modulation of hyperinflammation induced by SARS-CoV-2 infection: A perspective for COVID-19 therapy

A Hasankhani, A Bahrami, B Tavakoli-Far… - Frontiers in …, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a severe respiratory disease caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the lower …

Vitamin D supplementation as a rational pharmacological approach in the COVID-19 pandemic

L Ferder, VM Martín Giménez… - … of Physiology-Lung …, 2020 - journals.physiology.org
The COVID-19 pandemic has reached most of the countries worldwide causing death, which
often results from an inflammatory storm associated with severe acute respiratory syndrome …

Direct and indirect effects of COVID-19 in frail elderly: interventions and recommendations

MG Pizano-Escalante, LM Anaya-Esparza… - Journal of Personalized …, 2021 - mdpi.com
Frailty is a state of vulnerability to stressors because of a decreased physiological reserve,
resulting in poor health outcomes. This state is related to chronic conditions, many of which …