Background There is a substantial variation in rates of preterm delivery between different
parts of the world. The understanding of these variations, as well as the biological …

Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes …

Cytokines, including interleukins, interferons, tumor necrosis factors, and chemokines, have
a variety of pro‐and anti‐inflammatory effects in the body through a number of biochemical …

Evidence from family and twin-based studies provide strong support for a significant
contribution of maternal and fetal genetics to the timing of parturition and spontaneous …

Preterm birth which occurs before 37 weeks gestation is one of the most common obstetrical
complication in humans. After many studies, it appears that “not one answer fits all” …

Background Preterm prelabor rupture of the membranes (PPROM) is frequently complicated
by intraamniotic inflammatory processes such as intraamniotic infection and sterile …

Problem The inflammasome is implicated in the mechanisms that lead to spontaneous
preterm labor (PTL). However, whether there is inflammasome activation in the amniotic …

Background Recent studies on clinical chorioamnionitis at term suggest that some patients
with this diagnosis have neither intraamniotic infection nor intraamniotic inflammation. A …

Background Cervical insufficiency is a risk factor for spontaneous midtrimester abortion or
early preterm birth. Intra-amniotic infection has been reported in 8-52% of such patients and …

Ziel Offizielle Leitlinie der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe
(DGGG), der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (ÖGGG) und …