Subtype diagnosis of primary aldosteronism: is adrenal vein sampling always necessary?

F Buffolo, S Monticone, TA Williams, D Rossato… - International journal of …, 2017 - mdpi.com
Aldosterone producing adenoma and bilateral adrenal hyperplasia are the two most
common subtypes of primary aldosteronism (PA) that require targeted and distinct …

Cortisol co-secretion and clinical usefulness of ACTH stimulation test in primary aldosteronism: a systematic review and biases in epidemiological studies

K Inoue, T Kitamoto, Y Tsurutani, J Saito… - Frontiers in …, 2021 - frontiersin.org
The hypothalamus-pituitary-adrenal (HPA) axis plays an important role in primary
aldosteronism. Aldosterone biosynthesis is regulated not only by angiotensin II in the renin …

Postoperative ACTH-stimulated aldosterone predicts biochemical outcome in primary aldosteronism

D Bruedgam, C Adolf, H Schneider… - European Journal of …, 2023 - academic.oup.com
Objective Primary aldosteronism (PA) is the most common surgically curable cause of
hypertension. Unilateral aldosterone-producing adenoma can be treated with …

Predicting bilateral subtypes of primary aldosteronism without adrenal vein sampling: a systematic review and meta-analysis

E Ng, SM Gwini, W Zheng, PJ Fuller… - The Journal of Clinical …, 2024 - academic.oup.com
Context Primary aldosteronism (PA) is the most common endocrine cause of hypertension.
The final diagnostic step involves subtyping, using adrenal vein sampling (AVS), to …

A novel clinical nomogram to predict bilateral hyperaldosteronism in Chinese patients with primary aldosteronism

L Xiao, Y Jiang, C Zhang, L Jiang, W Zhou… - Clinical …, 2019 - Wiley Online Library
Context Adrenal venous sampling (AVS) is recommended as the gold standard for subtype
classification in primary aldosteronism (PA); however, this approach has limited availability …

Association of achieved blood pressure after treatment for primary aldosteronism with long-term kidney function

T Haze, Y Yano, Y Hatano, K Tamura… - Journal of Human …, 2022 - nature.com
Little is known regarding the association of blood pressure (BP) after treatment for primary
aldosteronism (PA)(ie, adrenalectomy and mineralocorticoid receptor antagonists) with long …

Clinical utility of the adrenocorticotropin stimulation test with/without dexamethasone suppression for definitive and subtype diagnosis of primary aldosteronism

K Inoue, M Omura, C Sugisawa, Y Tsurutani… - International Journal of …, 2017 - mdpi.com
The adrenocorticotropin (ACTH) stimulation test (AST) has been reported to be useful for
diagnosing primary aldosteronism (PA), particularly for differentiating PA subtypes under 1 …

Efficient screening of patients with aldosterone-producing adenoma using the ACTH stimulation test

T Kita, E Furukoji, T Sakae, K Kitamura - Hypertension Research, 2019 - nature.com
Adrenal venous sampling (AVS) is the gold standard test for distinguishing between
unilateral and bilateral primary aldosteronism (PA); however, AVS requires advanced and …

Use of peripheral plasma aldosterone concentration and response to ACTH during simultaneous bilateral adrenal veins sampling to predict the source of aldosterone …

M St‐Jean, I Bourdeau, É Therasse… - Clinical …, 2020 - Wiley Online Library
Context Previous studies suggested that plasma aldosterone (PAC) response to ACTH
stimulation could predict the subtypes of primary aldosteronism (PA) and avoid adrenal …

Plasma aldosterone response to ACTH stimulation test for diagnosis of primary aldosteronism: a cross-sectional study

W Manosroi, P Atthakomol, P Inthaphan… - BMC Endocrine …, 2024 - Springer
Background The diagnosis of primary aldosteronism (PA) requires screening and
confirmation testing. The present study examined whether the 1 µg ACTH stimulation test for …