[HTML][HTML] Long COVID: pathophysiological factors and abnormalities of coagulation

S Turner, MA Khan, D Putrino, A Woodcock… - Trends in Endocrinology …, 2023 - cell.com
Acute COVID-19 infection is followed by prolonged symptoms in approximately one in ten
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …

Diagnosis and management of post-COVID (long COVID) in children: a moving target

R Morello, L Martino, D Buonsenso - Current Opinion in Pediatrics, 2023 - journals.lww.com
Diagnosis and management of post-COVID (Long COVID) in child... : Current Opinion in
Pediatrics Diagnosis and management of post-COVID (Long COVID) in children: a moving target …

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also …

A Kruger, M Vlok, S Turner, C Venter… - Cardiovascular …, 2022 - Springer
Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID,
has become a major global health and economic burden. Previously, we provided evidence …

Laboratory findings and biomarkers in Long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?

DB Kell, E Pretorius - Biochemical Journal, 2023 - portlandpress.com
It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …

Increased levels of inflammatory and endothelial biomarkers in blood of long COVID patients point to thrombotic endothelialitis

S Turner, CA Naidoo, TJ Usher… - … in Thrombosis and …, 2024 - thieme-connect.com
The prevailing hypotheses for the persistent symptoms of Long COVID have been narrowed
down to immune dysregulation and autoantibodies, widespread organ damage, viral …

Using cardiorespiratory fitness assessment to identify pathophysiology in long COVID–Best practice approaches

MA Faghy, C Dalton, R Duncan, R Arena… - Progress in …, 2024 - Elsevier
Cardio-respiratory fitness (CRF) is well-established in the clinical domains as an integrative
measure of the body's physiological capability and capacity to transport and utilise oxygen …

Lung perfusion assessment in children with long‐COVID: A pilot study

DA Pizzuto, D Buonsenso, R Morello… - Pediatric …, 2023 - Wiley Online Library
Background There is increasing evidence that chronic endotheliopathy can play a role in
patients with Post‐Covid Condition (PCC, or Long Covid) by affecting peripheral …

Persistent respiratory symptoms associated with post-Covid condition (Long Covid) in children: a systematic review and analysis of current gaps and future …

L Martino, R Morello, C De Rose… - Expert Review of …, 2023 - Taylor & Francis
Introduction There is increasing evidence that also children can develop Long Covid.
However, there are no specific reviews providing a clear description of reported respiratory …

A perspective on how fibrinaloid microclots and platelet pathology may be applied in clinical investigations

E Pretorius, DB Kell - Seminars in Thrombosis and Hemostasis, 2023 - thieme-connect.com
Microscopy imaging has enabled us to establish the presence of fibrin (ogen) amyloid
(fibrinaloid) microclots in a range of chronic, inflammatory diseases. Microclots may also be …