Genomes usually contain some non-repetitive sequences that are missing from the
reference genome and occur only in a population subset. Such non-repetitive, non …

Puberty marks the end of childhood and is a period when individuals undergo physiological
and psychological changes to achieve sexual maturation and fertility. The onset of puberty is …

Adult height is a classic polygenic trait of high narrow-sense heritability (h 2= 0.8). In the late
nineteenth to early twentieth century, variation in adult height was used as a model to set the …

There is substantial genetic variation for common traits associated with reproductive lifespan
and for common diseases influencing female fertility. Progress in high-throughput …

In primates, puberty is unleashed by increased GnRH release from the hypothalamus
following an interval of juvenile quiescence. GWAS implicates Zinc finger (ZNF) genes in …

Age at menarche (AAM) has been reported to be associated with the risk of cardiovascular
disease (CVD), but the shape of and the mechanisms behind this association remain …

Puberty in humans is defined as the period of becoming capable of reproducing. It is marked
by maturation of the genital organs, development of secondary sex characteristics …

Background: Identifying reproductive risk factors in women offers a life course approach to
obesity and cardiovascular disease prevention. The association of female reproductive …

Aims/hypothesis The aim of this study was to examine the association between age at
menarche and prediabetes as well as diabetes, considering confounding factors and the …

Puberty has long been recognised as a difficult and upsetting process for individuals and
families, but it is now also being widely described as in crisis. Reportedly occurring earlier …