Background The changes that occur during puberty have been implicated in susceptibility to
a wide range of diseases later in life, many of which are characterized by sex-specific …

The timing of puberty has considerable biological, psychosocial and long-term health
implications. Secular trends in age at pubertal development, the effects of obesity and the …

Population studies elucidating the genetic architecture of reproductive ageing have been
largely limited to European ancestries, restricting the generalizability of the findings and …

Several genome-wide studies have identified loci associated with reproductive traits, such
as ages of menarche and menopause, in women of European ancestry. In this study, we …

Background Previous studies of mostly Western women have reported inconsistent findings
on the association between age at menarche and risk of cardiovascular disease (CVD) …

Human life-history traits (growth, maturation, nutritional status) are increasingly associated
with risk of chronic degenerative disease. Twin studies suggest high heritability of such …

Age at menarche (AM) and age at natural menopause (ANM) are complex traits with a high
heritability. Abnormal timing of menarche or menopause is associated with a reduced span …

Abstract Study Objective To analyze age at menarche and its association with excess weight
and body fat percentage. Design School-based cross-sectional survey. Setting …

STUDY QUESTION Do genetic associations identified in genome-wide association studies
(GWAS) of age at menarche (AM) and age at natural menopause (ANM) replicate in women …

The social sciences have been reticent to integrate a biodemographic approach to the study
of fertility choice and behaviour, resulting in theories and findings that are largely socially …