The language network as a natural kind within the broader landscape of the human brain

E Fedorenko, AA Ivanova, TI Regev - Nature Reviews Neuroscience, 2024 - nature.com
Abstract Language behaviour is complex, but neuroscientific evidence disentangles it into
distinct components supported by dedicated brain areas or networks. In this Review, we …

Asymmetry in the central nervous system: A clinical neuroscience perspective

A Mundorf, J Peterburs, S Ocklenburg - Frontiers in systems …, 2021 - frontiersin.org
Recent large-scale neuroimaging studies suggest that most parts of the human brain show
structural differences between the left and the right hemisphere. Such structural hemispheric …

Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes

V Warrier, EM Stauffer, QQ Huang, EM Wigdor… - Nature …, 2023 - nature.com
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …

Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification

N Okada, M Fukunaga, K Miura, K Nemoto… - Molecular …, 2023 - nature.com
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using
the current diagnostic system based on presenting symptoms and signs. The creation of a …

Language network lateralization is reflected throughout the macroscale functional organization of cortex

L Labache, T Ge, BTT Yeo, AJ Holmes - Nature communications, 2023 - nature.com
Hemispheric specialization is a fundamental feature of human brain organization. However,
it is not yet clear to what extent the lateralization of specific cognitive processes may be …

Heritability and cross-species comparisons of human cortical functional organization asymmetry

B Wan, Ş Bayrak, T Xu, HL Schaare, RAI Bethlehem… - Elife, 2022 - elifesciences.org
The human cerebral cortex is symmetrically organized along large-scale axes but also
presents inter-hemispheric differences in structure and function. The quantified contralateral …

Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

D Schijven, MC Postema… - Proceedings of the …, 2023 - National Acad Sciences
Left–right asymmetry is an important organizing feature of the healthy brain that may be
altered in schizophrenia, but most studies have used relatively small samples and …

The enigma and implications of brain hemispheric asymmetry in neurodegenerative diseases

N Lubben, E Ensink, GA Coetzee… - Brain …, 2021 - academic.oup.com
The lateralization of the human brain may provide clues into the pathogenesis and
progression of neurodegenerative diseases. Though differing in their presentation and …

Evolution of Human Brain Left–Right Asymmetry: Old Genes with New Functions

J Wang, S Ma, P Yu, X He - Molecular Biology and Evolution, 2023 - academic.oup.com
The human brain is generally anatomically symmetrical, boasting mirror-like brain regions in
the left and right hemispheres. Despite this symmetry, fine-scale structural asymmetries are …

Dissociable brain structural asymmetry patterns reveal unique phenome-wide profiles

K Saltoun, R Adolphs, LK Paul, V Sharma… - Nature Human …, 2023 - nature.com
Broca reported~ 150 years ago that particular lesions of the left hemisphere impair speech.
Since then, other brain regions have been reported to show lateralized structure and …