Imaging and postmortem studies have revealed disturbed oligodendroglia-related
processes in patients with schizophrenia and provided much evidence for disturbed …

Twin studies of psychiatric disorders such as schizophrenia and autism spectrum disorder
have employed epidemiological approaches that determine heritability by comparing the …

Brain morphology differs markedly between individuals with schizophrenia, but the cellular
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …

Schizophrenia (SCZ) is a highly heterogeneous disorder with diverse clinical manifestations
and macro-and microscale biological variations, usually observed at dissociable levels …

Abstract Background Circular RNAs (circRNAs), a novel class of poorly conserved non-
coding RNAs that regulate gene expression, are highly enriched in the human brain …

Oligodendrocytes are the glial cells responsible for the formation of the myelin sheath
around axons. During neurodevelopment, oligodendrocytes undergo maturation and …

Bisphenol A (BPA) is considered as one of the most extensively synthesized and used
chemicals for industrial and consumer products. Previous investigations have established …

Introduction Treatment of severe mental illness (SMI) symptoms, especially negative
symptoms and cognitive dysfunction in schizophrenia, remains a major unmet need. There …

Progress in iPSC-based cellular systems provides new insights into human brain
development and early neurodevelopmental deviations in psychiatric disorders. Among …

Oligodendrocytes (OLs) are critical for myelination and are implicated in several brain
disorders. Directed differentiation of human-induced OLs (iOLs) from pluripotent stem cells …