Photovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas

NAL Chenais, MJI Airaghi Leccardi… - Communications …, 2021 - nature.com
Retinal prostheses hold the promise of restoring vision in totally blind people. However, a
decade of clinical trials highlighted quantitative limitations hampering the possibility of …

A fully organic retinal prosthesis restores vision in a rat model of degenerative blindness

JF Maya-Vetencourt, D Ghezzi, MR Antognazza… - Nature materials, 2017 - nature.com
The degeneration of photoreceptors in the retina is one of the major causes of adult
blindness in humans. Unfortunately, no effective clinical treatments exist for the majority of …

Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS

K Stingl, KU Bartz-Schmidt, D Besch… - … of the Royal …, 2013 - royalsocietypublishing.org
This study aims at substituting the essential functions of photoreceptors in patients who are
blind owing to untreatable forms of hereditary retinal degenerations. A microelectronic …

Bioengineering strategies for restoring vision

J Cehajic-Kapetanovic, MS Singh, E Zrenner… - Nature biomedical …, 2023 - nature.com
Late-stage retinal degenerative disease involving photoreceptor loss can be treated by
optogenetic therapy, cell transplantation and retinal prostheses. These approaches aim to …

Clinical characteristics and current therapies for inherited retinal degenerations

JA Sahel, K Marazova, I Audo - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Inherited retinal degenerations (IRDs) encompass a large group of clinically and genetically
heterogeneous diseases that affect approximately 1 in 3000 people (> 2 million people …

[HTML][HTML] Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa

TL Edwards, CL Cottriall, K Xue, MP Simunovic… - Ophthalmology, 2018 - Elsevier
Purpose To report the initial efficacy results of the Retina Implant Alpha AMS (Retina Implant
AG, Reutlingen, Germany) for partial restoration of vision in end-stage retinitis pigmentosa …

Wireless Battery-free and Fully Implantable Organ Interfaces

A Bhatia, J Hanna, T Stuart, KA Kasper… - Chemical …, 2024 - ACS Publications
Advances in soft materials, miniaturized electronics, sensors, stimulators, radios, and battery-
free power supplies are resulting in a new generation of fully implantable organ interfaces …

Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina

A Sengupta, A Chaffiol, E Macé, R Caplette… - EMBO molecular …, 2016 - embopress.org
Targeting the photosensitive ion channel channelrhodopsin‐2 (ChR2) to the retinal circuitry
downstream of photoreceptors holds promise in treating vision loss caused by retinal …

[HTML][HTML] Sensory substitution: Closing the gap between basic research and widespread practical visual rehabilitation

S Maidenbaum, S Abboud, A Amedi - Neuroscience & Biobehavioral …, 2014 - Elsevier
Sensory substitution devices (SSDs) have come a long way since first developed for visual
rehabilitation. They have produced exciting experimental results, and have furthered our …

2D semiconductor based flexible photoresponsive ring oscillators for artificial vision pixels

N Li, Q Wang, C He, J Li, X Li, C Shen, B Huang… - ACS …, 2023 - ACS Publications
Artificial retina implantation provides an effective and feasible attempt for vision recovery in
addition to retinal transplantation. The most advanced artificial retinas ever developed …