This review describes the organization and importance of mucus in the intestine and lungs
in relation to the diseases cystic fibrosis (CF), ulcerative colitis and chronic obstructive …

Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene
cause CF. Infants with CFTR mutations show a peribronchial neutrophil infiltration prior to …

Rationale: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) was shown to be efficacious and
safe in patients≥ 12 years of age with cystic fibrosis and at least one F508del-CFTR (cystic …

Objective Cystic fibrosis (CF), caused by mutations in the CF transmembrane conductance
regulator (CFTR) gene, continues to present diagnostic challenges. Newborn screening and …

Background A series of phase 3 clinical trials have demonstrated that elexacaftor plus
tezacaftor plus ivacaftor (ELX/TEZ/IVA) is safe and efficacious in people with cystic fibrosis …

Rationale: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) has been shown to be safe and
effective in people with cystic fibrosis (CF) aged⩾ 6 years with at least one F508del-CFTR …

Stretchable and wearable sensors allow intimate integration with the human body for health
and fitness monitoring. In addition to the acquisition of various physical parameters …

Background The efficacy, safety, and tolerability of lumacaftor and ivacaftor are established
in patients aged 6 years and older with cystic fibrosis, homozygous for the F508del-CFTR …

Rationale: Combination lumacaftor/ivacaftor has been shown to improve lung function and
other endpoints in patients aged 12 years and older with cystic fibrosis and homozygous for …

This paper introduces super absorbent polymer valves and colorimetric sensing reagents as
enabling components of soft, skin‐mounted microfluidic devices designed to capture, store …