Regulatory roles of flavonoids in caspase-11 non-canonical inflammasome-mediated inflammatory responses and diseases

YS Yi - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammasomes are multiprotein complexes that activate inflammatory responses by
inducing pyroptosis and secretion of pro-inflammatory cytokines. Along with many previous …

[HTML][HTML] Impact of polyphenols on heart failure and cardiac hypertrophy: clinical effects and molecular mechanisms

N Hedayati, A Yaghoobi, M Salami… - Frontiers in …, 2023 - frontiersin.org
Polyphenols are abundantly present in regular diets and possess antioxidant, anti-
inflammatory, anti-cancer, neuroprotective, and cardioprotective effects. Regarding the …

Kaempferol improves exercise performance by regulating glucose uptake, mitochondrial biogenesis, and protein synthesis via PI3K/AKT and MAPK signaling …

X Ji, C Zhang, J Yang, Y Tian, L You, H Yang, Y Li… - Foods, 2024 - mdpi.com
Kaempferol is a natural flavonoid with reported bioactivities found in many fruits, vegetables,
and medicinal herbs. However, its effects on exercise performance and muscle metabolism …

Key ingredients in Verbena officinalis and determination of their anti-atherosclerotic effect using a computer-aided drug design approach

Y Chen, Y Gan, J Yu, X Ye, W Yu - Frontiers in Plant Science, 2023 - frontiersin.org
Lipid metabolism disorders may considerably contribute to the formation and development
of atherosclerosis (AS). Traditional Chinese medicine has received considerable attention in …

The role of kaempferol in gynaecological malignancies: progress and perspectives

X Ma, X Zhang, X Wang, C Wang, Y Ma - Frontiers in Pharmacology, 2023 - frontiersin.org
Kaempferol, a flavonoid derived from various herbs such as cocoyam, propolis, and
grapefruit, has garnered interest due to its numerous pharmacological benefits, including …

Visualizing the distribution of flavonoids in litchi (Litchi chinenis) seeds through matrix-assisted laser desorption/ionization mass spectrometry imaging

Y Liu, X Nie, J Wang, Z Zhao, Z Wang… - Frontiers in Plant Science, 2023 - frontiersin.org
Flavonoids are one of the most important bioactive components in litchi (Litchi chinensis
Sonn.) seeds and have broad-spectrum antiviral and antitumor activities. Litchi seeds have …

Fermented Sprouts of Codonopsis lanceolata Suppress LPS-Induced Inflammatory Responses by Inhibiting NF-κB Signaling Pathway in RAW 264.7 Macrophages …

SH Choi, SY Kim, KM Kim, TJ Mony, HJ Bae, MS Kim… - Pharmaceutics, 2023 - mdpi.com
The interest in bioconversion through fermentation of sprouts produced in smart farms is
increasing due to their potential health benefits. Codonopsis lanceolata (CL) is reported to …

Advances and prospects of natural dietary polyphenols as G-quadruplex stabilizers in biomedical applications

H Ye, H Zhang, J Xiang, G Shen, F Yang… - International Journal of …, 2023 - Elsevier
Abstract G-quadruplexes (G4s) have arrested continuous interest in cancer research, and
targeting G4s with small molecules has become an ideal approach for drug development …

Comparative analysis of fatty acids, volatile and non-volatile components in red huajiao (Zanthoxylum bungeanum maxim.) and green huajiao (Zanthoxylum armatum …

C Zhao, M Han, T Tu, S Chen, W Hu, L Dong… - Industrial Crops and …, 2023 - Elsevier
In China, huajiao, a traditional industrial crop, is categorized as red huajiao (RHJ;
Zanthoxylum bungeanum maxim.) and green huajiao (GHJ; Zanthoxylum armatum DC.) …

Potential effect of kaempferol against various malignancies: recent advances and perspectives

M Shahbaz, M Imran, U Momal, H Naeem… - Food and Agricultural …, 2023 - Taylor & Francis
Kaempferol is a flavonoid present in many eatable plants. Researchers discovered a link
between consuming foods high in kaempferol and lowering the threat for acquiring many …