Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis

CT Baldari, A Onnis, E Andreano, G Del Giudice… - Trends in …, 2023 - cell.com
The COVID-19 pandemic, caused by SARS-CoV-2, has caused an estimated 5 billion
infections and 20 million deaths by respiratory failure. In addition to the respiratory disease …

COVID-19, SARS-CoV-2 vaccination, and human herpesviruses infections

PAC Maple - Vaccines, 2023 - mdpi.com
There are several human herpesviruses. A common characteristic of infection by these
viruses is latency, by which the virus assumes a non-replicative state, subverting the …

Viral reactivation in the lungs of patients with severe pneumonia is associated with increased mortality, a multicenter, retrospective study

L Huang, X Zhang, L Pang, P Sheng… - Journal of Medical …, 2023 - Wiley Online Library
Viral reactivation is widespread in patients with severe pneumonia, yet the landscape of viral
reactivation in the lungs is not well‐known. This study aims to assess the landscape and …

COVID-19 and Alzheimer's disease: what is the connection?

RF Itzhaki - Journal of Alzheimer's Disease, 2023 - content.iospress.com
Wang et al. found that elderly COVID-19 patients were at risk of AD. The following facts
suggest a possible explanation: reactivation of herpes simplex virus type 1 (HSV1) and other …

AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1

H Doshi, K Spengler, A Godbole, YS Gee… - Microbiology …, 2023 - Am Soc Microbiol
Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing
mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon …

Pulmonary herpes simplex virus and cytomegalovirus in patients with acute respiratory distress syndrome related to COVID-19

LS Boers, F van Someren Gréve, JM van Hattem… - Intensive Care …, 2024 - Springer
Purpose Human herpesviruses, particularly cytomegalovirus (CMV) and herpes simplex
virus (HSV), frequently reactivate in critically ill patients, including those with acute …

Low Prevalence of HSV-1 and Helicobacter pylori in HNSCC and Chronic Tonsillitis Patients Compared to Healthy Individuals

JK Strzelczyk, A Świętek, D Hudy, K Gołąbek… - Diagnostics, 2023 - mdpi.com
Recent studies identified viral and bacterial factors, including HSV-1 and H. pylori, as
possible factors associated with diseases such as chronic tonsillitis and cancers, including …

Updates in the management of respiratory virus infections in ICU patients: revisiting the non-SARS-CoV-2 pathogens

O Saura, J Chommeloux, D Levy… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Although viruses are an underestimated cause of community-acquired
pneumonias (CAP) and hospital-acquired pneumonias (HAP)/ventilator-associated …

SARS-CoV-2 Induced Herpes Virus Reactivations and Related Implications in Oncohematology: When Lymphocytopenia Sets in and Immunosurveillance Drops Out

L Roncati, E Sweidan, C Tchawa, G Gianotti… - Microorganisms, 2023 - mdpi.com
The severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2), is a positivesense
single-stranded ribonucleic acid (RNA) virus contagious in humans and responsible for the …

Herpesvirus reactivation in respiratory tract is associated with increased mortality of severe pneumonia patients and their respiratory microbiome dysbiosis

Y Liu, Z Wen, Y Fang, T Wang, F Wu… - Frontiers in Cellular …, 2023 - frontiersin.org
Severe pneumonia (SP) is a respiratory tract disease that seriously threatens human health.
The herpesvirus detected in patients, especially with severe and immunodeficient diseases …