Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics

S Stelloo, MT Alejo-Vinogradova, CAGH van Gelder… - Cell Stem Cell, 2024 - cell.com
Gastrulation is a critical stage in embryonic development during which the germ layers are
established. Advances in sequencing technologies led to the identification of gene …

[HTML][HTML] 动物早期胚胎发育中表观重编程的机制

余彤, 任斌斌, 郑睿智, 朱文治, 苏建民 - 畜牧兽医学报, 2023 - html.rhhz.net
哺乳动物早期胚胎发育过程中, 受精卵经历了一系列表观遗传重编程事件,
去除了雌雄原核的表观遗传记忆, 从而建立了胚胎的全能性. 然而, 这些重编程事件的进行必须 …

Cloning by SCNT: Integrating Technical and Biology-Driven Advances

MT Moura - Somatic Cell Nuclear Transfer Technology, 2023 - Springer
Somatic cell nuclear transfer (SCNT) into enucleated oocytes initiates nuclear
reprogramming of lineage-committed cells to totipotency. Pioneer SCNT work culminated …

[PDF][PDF] Spatiotemporal architecture of mouse embryogenesis at single-cell resolution

A Sampath Kumar - 2023 - depositonce.tu-berlin.de
The development of an entire organism from a single-cell zygote remains a fascinating and
fundamental question in biology. The single-cell zygote proceeds through numerous …