RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …

Cancer was initially considered to be an exclusively genetic disease, but an interplay of
dysregulated genetic and epigenetic mechanisms is now known to contribute to the cancer …

Chemical modifications to nucleic acids occur across the kingdoms of life and carry
important regulatory information. Reliable high-resolution mapping of these modifications is …

Epitranscriptomic modification of RNA regulates human development, health, and disease.
The true diversity of the transcriptome in breast cancer including chemical modification of …

RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …

A common mRNA modification is 5-methylcytosine (m 5 C), whose role in gene-transcript
processing and cancer remains unclear. Here, we identify serine/arginine-rich splicing factor …

Icariin (ICA) is a kind of natural flavonoid compound monomer, which is derived from the
extract of dried stems and leaves of Epimedium. Modern pharmacological studies have …

Background The precise temporal and spatial regulation of N5‐methylcytosine (m5C) RNA
modification plays essential roles in RNA metabolism, and is necessary for the maintenance …