Single-cell RNA sequencing (scRNA-seq) has been developed for characterizing the
transcriptome of cells that are rare but of biological significance. With cell barcoding and …

Breakthroughs in the development of high-throughput technologies for profiling
transcriptomes at the single-cell level have helped biologists to understand the …

Aging increases the risk of liver diseases and systemic susceptibility to aging-related
diseases. However, cell type-specific changes and the underlying mechanism of liver aging …

Brown adipose tissue is well known to be a thermoregulatory organ particularly important in
small rodents and human infants, but it was only recently that its existence and significance …

Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas
(UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had …

Cancer has become one of the greatest threats to human health, and new technologies are
urgently needed to further clarify the mechanisms of cancer so that better detection and …

Uveitis is a severe autoimmune disease, and a common cause of blindness; however, its
individual cellular dynamics and pathogenic mechanism remain poorly understood. Herein …

Single-cell and spatial transcriptomics have diverted researchers' attention from the
multicellular level to the single-cell level and spatial information. Single-cell transcriptomes …

Vitreous fibrovascular membranes (FVMs), the hallmark of proliferative diabetic retinopathy
(PDR), cause retinal hemorrhage, detachment, and eventually blindness. However, little is …

Aims Coronary vasculature formation is a critical event during cardiac development,
essential for heart function throughout perinatal and adult life. However, current …